Substantial advances have been made recently in the pathobiology of pituitary tumors.
Similar to many other endocrine tumors, over the last few years we have recognized the role …

The tumour microenvironment (TME) includes a variety of non-neoplastic cells and non-
cellular elements such as cytokines, growth factors and enzymes surrounding tumour cells …

The prevalence of symptomatic pituitary neuroendocrine tumors (PitNETs) is approximately
1 in 1000 in the general population. Most of these tumors occur sporadically and are not part …

Genetic testing is becoming part of mainstream endocrinology. An increasing number of rare
and not-so-rare endocrine diseases have an identifiable genetic cause, either at the …

Abstract Carney complex (CΝC) is a very rare, autosomal dominant, hereditary syndrome.
Seventy percent of individuals with CNC have germline inactivating or deleting mutations of …

Introduction: This study described a Chinese case of X-linked acrogigantism (X-LAG) and
summarized the characteristics and treatment of all reported cases. Methods: Clinical …

ABSTRACT Familial Isolated Pituitary Adenoma (FIPA) is a term used to identify a genetic
condition with pituitary tumors without other endocrine or other associated abnormalities …

Children born with deleterious biallelic variants of the chaperone aryl hydrocarbon receptor
interacting protein (AIP) have a novel pediatric metabolic disease presenting a severe …

Growth hormone (GH) excess secondary to a pituitary adenoma may lead to gigantism in
children and adolescents. Most pituitary tumors occur sporadically; however, in about half of …

Disease of the pituitary may negatively affect patients in multiple ways. The present thesis
evaluates four aspects of surgical outcome in patient's presenting with pituitary adenoma …