Inorganic nanomaterials with rapid clearance for biomedical applications
Inorganic nanomaterials that have inherently exceptional physicochemical properties (eg,
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
catalytic, optical, thermal, electrical, or magnetic performance) that can provide desirable …
[HTML][HTML] DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
RX Huang, PK Zhou - Signal transduction and targeted therapy, 2020 - nature.com
Radiotherapy is one of the most common countermeasures for treating a wide range of
tumors. However, the radioresistance of cancer cells is still a major limitation for …
tumors. However, the radioresistance of cancer cells is still a major limitation for …
The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression
Ferroptosis, a form of regulated cell death caused by lipid peroxidation, was recently
identified as a natural tumor suppression mechanism. Here, we show that ionizing radiation …
identified as a natural tumor suppression mechanism. Here, we show that ionizing radiation …
Inflammatory microenvironment remodelling by tumour cells after radiotherapy
M McLaughlin, EC Patin, M Pedersen, A Wilkins… - Nature Reviews …, 2020 - nature.com
The development of immune checkpoint inhibitors (ICIs) is revolutionizing the way we think
about cancer treatment. Even so, for most types of cancer, only a minority of patients …
about cancer treatment. Even so, for most types of cancer, only a minority of patients …
Artificial intelligence in radiation oncology
Artificial intelligence (AI) has the potential to fundamentally alter the way medicine is
practised. AI platforms excel in recognizing complex patterns in medical data and provide a …
practised. AI platforms excel in recognizing complex patterns in medical data and provide a …
Ferroptosis, radiotherapy, and combination therapeutic strategies
Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …
Advances and perspectives in organic sonosensitizers for sonodynamic therapy
X Xing, S Zhao, T Xu, L Huang, Y Zhang, M Lan… - Coordination Chemistry …, 2021 - Elsevier
Sonodynamic therapy (SDT), which involves a combination of low-intensity ultrasound (US)
and a chemical sonosensitizer, has emerged as a promising minimally invasive and …
and a chemical sonosensitizer, has emerged as a promising minimally invasive and …
Radiation therapy‐associated toxicity: Etiology, management, and prevention
K Wang, JE Tepper - CA: A Cancer Journal for Clinicians, 2021 - Wiley Online Library
Radiation therapy (RT) is a curative treatment for many malignancies and provides effective
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …
ROS signalling in the biology of cancer
JN Moloney, TG Cotter - Seminars in cell & developmental biology, 2018 - Elsevier
Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …
and has been shown to have several roles, for example, they can activate pro-tumourigenic …
Hypofractionated FLASH-RT as an Effective Treatment against Glioblastoma that Reduces Neurocognitive Side Effects in MiceSparing the Cognition, not the Tumor …
P Montay-Gruel, MM Acharya, P Gonçalves Jorge… - Clinical Cancer …, 2021 - AACR
Purpose: Recent data have shown that single-fraction irradiation delivered to the whole
brain in less than tenths of a second using FLASH radiotherapy (FLASH-RT), does not elicit …
brain in less than tenths of a second using FLASH radiotherapy (FLASH-RT), does not elicit …