Recent developments in liposomes, microparticles and nanoparticles for protein and peptide drug delivery

ML Tan, PFM Choong, CR Dass - Peptides, 2010 - Elsevier
Proteins and peptides are increasingly recognized as potential leads for the development of
new therapeutics for a variety of human ailments. Due to their relatively specific mode of …

Drug carriers for the delivery of therapeutic peptides

AW Du, MH Stenzel - Biomacromolecules, 2014 - ACS Publications
Peptides take on an increasingly important role as therapeutics in areas including diabetes,
oncology, and metabolic, cardiovascular, and infectious diseases. In addition, many …

[HTML][HTML] Treatment of allergic asthma: modulation of Th2 cells and their responses

B Bosnjak, B Stelzmueller, KJ Erb, MM Epstein - Respiratory research, 2011 - Springer
Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent
episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory …

Exosomes from bronchoalveolar fluid of tolerized mice prevent allergic reaction

N Prado, EG Marazuela, E Segura… - The Journal of …, 2008 - journals.aai.org
Exosomes are nanovesicles originating from multivesicular bodies that are secreted by a
variety of cell types. The dual capability of exosomes to promote immunity or to induce …

In vivo reprogramming of immune cells: technologies for induction of antigen-specific tolerance

RM Pearson, LM Casey, KR Hughes, SD Miller… - Advanced drug delivery …, 2017 - Elsevier
Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …

Recent advances in the use of nanoparticles for allergen‐specific immunotherapy

H Pohlit, I Bellinghausen, H Frey, J Saloga - Allergy, 2017 - Wiley Online Library
The number of patients suffering from allergic asthma and rhinoconjunctivitis has increased
dramatically within the last decades. Allergen‐specific immunotherapy (AIT) is the only …

The spectrum of olive pollen allergens. From structures to diagnosis and treatment

M Villalba, R Rodríguez, E Batanero - Methods, 2014 - Elsevier
Olive tree is one of the main allergy sources in Mediterranean countries. The identification of
the allergenic repertoire from olive pollen has been essential for the development of rational …

Allergen immunotherapy: progress and future outlook

L Šošić, M Paolucci, S Flory, F Jebbawi… - Expert Review of …, 2023 - Taylor & Francis
Introduction Allergy, the immunological hypersensitivity to innocuous environmental
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …

[HTML][HTML] Peptide allergen immunotherapy: A new perspective in olive-pollen allergy

D Calzada, L Cremades-Jimeno, M López-Ramos… - Pharmaceutics, 2021 - mdpi.com
Allergic diseases are highly prevalent disorders, mainly in industrialized countries where
they constitute a high global health problem. Allergy is defined as an immune response …

[HTML][HTML] PLGA, PLGA-TMC and TMC-TPP nanoparticles differentially modulate the outcome of nasal vaccination by inducing tolerance or enhancing humoral …

C Keijzer, B Slütter, R van der Zee, W Jiskoot… - PLoS …, 2011 - journals.plos.org
Development of vaccines in autoimmune diseases has received wide attention over the last
decade. However, many vaccines showed limited clinical efficacy. To enhance vaccine …