[HTML][HTML] ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways

A Treveil, B Bohar, P Sudhakar, L Gul… - PLOS Computational …, 2021 - journals.plos.org
The SARS-CoV-2 pandemic of 2020 has mobilised scientists around the globe to research
all aspects of the coronavirus virus and its infection. For fruitful and rapid investigation of …

M1 Macrophage-Targeted Curcumin Nanocrystals with l-Arginine-Modified for Acute Lung Injury by Inhalation

S Wu, P Guo, Q Zhou, X Yang, J Dai - Journal of Pharmaceutical Sciences, 2024 - Elsevier
Abstract Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) with clinical
manifestations of respiratory distress and hypoxemia remains a significant cause of …

[HTML][HTML] Looking at COVID-19 from a systems biology perspective

ES Turilli, M Lualdi, M Fasano - Biomolecules, 2022 - mdpi.com
The sudden outbreak and worldwide spread of the SARS-CoV-2 pandemic pushed the
scientific community to find fast solutions to cope with the health emergency. COVID-19 …

[HTML][HTML] An approach to cellular tropism of SARS-CoV-2 through protein–protein interaction and enrichment analysis

D Ortega-Bernal, S Zarate, MÁ Martinez-Cárdenas… - Scientific Reports, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is a primarily pulmonary disease that can affect
several organs, directly or indirectly. To date, there are many questions about the different …

[HTML][HTML] Interoperability of COVID-19 clinical phenotype data with host and viral genetics data

A Bernasconi, S Ceri - BioMed, 2022 - mdpi.com
The outbreak of the COVID-19 epidemic has focused enormous attention on the genetics of
viral infection and related disease. Since the beginning of the pandemic, we focused on the …

Prediction of viral-host interactions of COVID-19 by computational methods

TB Alakus, I Turkoglu - Chemometrics and Intelligent Laboratory Systems, 2022 - Elsevier
Experimental approaches are currently used to determine viral-host interactions, but these
approaches are both time-consuming and costly. For these reasons, computational-based …

[HTML][HTML] Deciphering the Genetic Variation: A Comparative Analysis of Parental and Attenuated Strains of the QXL87 Vaccine for Infectious Bronchitis

M Wang, Z Bo, C Zhang, M Guo, Y Wu, X Zhang - Animals, 2024 - mdpi.com
Simple Summary The live attenuated infectious bronchitis virus vaccine strain QXL87 was
derived from the parental virulent strain JS/2010/12 through serial passages in specific …

[HTML][HTML] SARS-CoV-2 Spatiotemporal Genomic and Molecular Analysis of the First Wave of the COVID-19 Pandemic in Macaé, the Brazilian Capital of Oil

B da-Costa-Rodrigues, C Cheohen… - International Journal of …, 2022 - mdpi.com
The SARS-CoV-2 virus infection led to millions of deaths during the COVID-19 pandemic.
Hundreds of workers from several other Brazilian cities, as well as from other countries …

Computational approaches for drug repositioning and repurposing to combat SARS-CoV-2 infection

S Panda, L Kumari, HR Badwaik… - … Approaches for Novel …, 2022 - Elsevier
Drug repositioning (also referred to as drug repurposing) is the method of exploring novel
therapeutic indications for Food and Drug Administration-approved clinically implemented …

Integrative COVID-19 biological network inference with probabilistic core decomposition

Y Guo, F Esfahani, X Shao, V Srinivasan… - Briefings in …, 2022 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for
millions of deaths around the world. To help contribute to the understanding of crucial …