Background: Several broad lines of evidence support the involvement of epigenetic
processes in neurodevelopment and psychiatric disorders. Epigenetic disruption also …

Objectives Focal cortical dysplasia (FCD) is a major cause of drug‐resistant focal epilepsy in
children, and the clinicopathological classification remains a challenging issue in daily …

Multiplex single-molecule fluorescent in situ hybridization (smFISH) is a powerful method for
validating RNA sequencing and emerging spatial transcriptomic data, but quantification …

Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease
presents with a complex spectrum of genomic aberrations, but the pharmacological …

Background Epigenetic studies that utilize peripheral tissues to identify molecular substrates
of neuropsychiatric disorders rely on the assumption that disease-relevant, cellular …

Alzheimer's disease (AD) is a large and growing public health problem. It is characterized by
the accumulation of amyloid-β peptides and abnormally phosphorylated tau proteins that are …

DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

Autism spectrum disorder (ASD) encompasses a collection of complex neuropsychiatric
disorders characterized by deficits in social functioning, communication and repetitive …

Epigenetic deregulation of α‐synuclein plays a key role in Parkinson's disease (PD).
Analysis of the SNCA promoter using the ENCODE database revealed the presence of …

Cancer is an aging‐associated disease, but the underlying molecular links between these
processes are still largely unknown. Gene promoters that become hypermethylated in aging …