Osteoarthritis (OA) is a complicated degenerative disease that affects whole joint tissue.
Currently, apart from surgical approaches to treat late stage OA, effective treatments to …

Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Metabolism is important for cartilage and synovial joint function. Under adverse
microenvironmental conditions, mammalian cells undergo a switch in cell metabolism from a …

Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …

Osteoarthritis (OA) is a common joint condition that is a leading cause of disability
worldwide. There are currently no disease-modifying treatments for osteoarthritis, which is …

Osteoimmunology is an interdisciplinary research field which combines the existing fields of
osteology (bone biology) and immunology under one umbrella. The observation that …

Osteoarthritis (OA) is a degenerative joint disease involving both cartilage and synovium.
The canonical Wnt/β-catenin pathway, which is activated in OA, is emerging as an important …

The infrapatellar pad, a fibro‐adipose tissue with peculiar microscopic and mechanical
features, is gaining wide attention in the field of rheumatological research. The purpose of …

The field of osteoarthritis (OA) biology is rapidly evolving and brilliant progress has been
made this year as well. Landmark studies of OA biology published in 2021 and early 2022 …

Structural damage of cartilage and bone tissue is a hallmark of rheumatoid arthritis (RA).
The resulting joint destruction constitutes one of the major disease consequences for …