Cancer patients are living longer. The sequelae of cancer treatment and the role of comorbid
conditions present before the diagnosis, such as CKD, have been increasingly recognized …

Creatinine clearance has been the most common method of estimating kidney function for
the purpose of drug dosing for decades. The availability and extensive clinical use of …

Background Obesity is associated with physiological changes that can affect drug
pharmacokinetics. Obese individuals are underrepresented in clinical trials, leading to a lack …

An accurate estimated glomerular filtration rate (eGFR) is essential in drug dosing. This
study demonstrates the limitations of indexed (ml/min/1.73 m2) and de‐indexed (ml/min) …

Despite the proven superiority of the Chronic Kidney Disease Epidemiology Collaboration
(CKD-EPI) over the Cockcroft–Gault (CG) formula, current guidelines recommend the latter …

International guidelines recommend the Chronic Kidney Disease Epidemiology
Collaboration (CKD-EPI) method to monitor kidney function in chronic kidney disease using …

How to adjust drug doses in chronic kidney disease - PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …

Rationale & Objective Recent studies evaluated and proposed new race-neutral, creatinine-
based glomerular filtration rate (GFR) estimation equations. The performance of these …

Purpose While doses of carboplatin are mostly individualized according to the Calvert
equation based on estimated Glomerular Filtration Rate (eGFR), there is still uncertainty …

ABSTRACT Background The Cockcroft–Gault equation (CrClC-G) is recommended for dose
adjustment of direct oral anticoagulant drugs (DOACs) to kidney function. We aimed to …