A dietary tomato supplement prevents prostate cancer in TRAMP mice
T Pannellini, M Iezzi, M Liberatore, F Sabatini… - Cancer prevention …, 2010 - AACR
Transgenic adenocarcinoma of the mouse prostate (TRAMP) is a model for progressive
prostate cancer that mirrors the stages of the human form. In this study, the effects of a diet …
prostate cancer that mirrors the stages of the human form. In this study, the effects of a diet …
Aggressive prostate cancer is prevented in ERαKO mice and stimulated in ERβKO TRAMP mice
A Ślusarz, GA Jackson, JK Day, NS Shenouda… - …, 2012 - academic.oup.com
Previous evidence suggests soy genistein may be protective against prostate cancer, but
whether this protection involves an estrogen receptor (ER)-dependent mechanism is …
whether this protection involves an estrogen receptor (ER)-dependent mechanism is …
[HTML][HTML] Dietary tomato inhibits angiogenesis in TRAMP prostate cancer but is not protective with a Western-style diet in this pilot study
Prostate cancer (PCa) remains the second most diagnosed cancer worldwide. Higher body
weight is associated with chronic inflammation, increased angiogenesis, and treatment …
weight is associated with chronic inflammation, increased angiogenesis, and treatment …
Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer
The telomerase reverse transcriptase, TERT, is an attractive target for human cancer
vaccination because its expression is reactivated in a conspicuous fraction of human tumors …
vaccination because its expression is reactivated in a conspicuous fraction of human tumors …
7-epi-nemorosone from Clusia rosea induces apoptosis, androgen receptor down-regulation and dysregulation of PSA levels in LNCaP prostate carcinoma cells
D Díaz-Carballo, S Gustmann, AH Acikelli… - Phytomedicine, 2012 - Elsevier
The aim of this work was to characterize the antitumoral activity of the plant compound 7-epi-
nemorosone in prostate carcinoma cell lines. Prostate cancer is the most frequently …
nemorosone in prostate carcinoma cell lines. Prostate cancer is the most frequently …
Differential effects of omega‐3 PUFAS on tumor progression at early and advanced stages in TRAMP mice
GM Amaro, ADT da Silva, GH Tamarindo… - The …, 2022 - Wiley Online Library
Background In vitro studies evidenced antitumor effects of omega‐3 polyunsaturated fatty
acids ([n− 3] PUFAs), but their effects on prostate cancer (PCa) remain controversial in …
acids ([n− 3] PUFAs), but their effects on prostate cancer (PCa) remain controversial in …
Autoimmune B-cell lymphopenia after successful adoptive therapy with telomerase-specific T lymphocytes
Telomerase reverse transcriptase (TERT) is a good candidate for cancer immunotherapy
because it is overexpressed in 85% of all human tumors and implicated in maintenance of …
because it is overexpressed in 85% of all human tumors and implicated in maintenance of …
[HTML][HTML] Genetic deletion of osteopontin in TRAMP mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers
G Mauri, E Jachetti, B Comuzzi, M Dugo, I Arioli… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Osteopontin (OPN) is a secreted glycoprotein, that belongs to the non-structural extracellular
matrix (ECM), and its over expression in human prostate cancer has been associated with …
matrix (ECM), and its over expression in human prostate cancer has been associated with …
Mice lacking β-carotene-15, 15'-dioxygenase exhibit reduced serum testosterone, prostatic androgen receptor signaling, and prostatic cellular proliferation
JW Smith, NA Ford, JM Thomas-Ahner… - American Journal …, 2016 - journals.physiology.org
β-Carotene-15, 15'-dioxygenase (BCO1) cleaves dietary carotenoids at the central 15,
15'double bond, most notably acting on β-carotene to yield retinal. However, Bco1 disruption …
15'double bond, most notably acting on β-carotene to yield retinal. However, Bco1 disruption …
Natural Compounds, Antioxidant and Antiandrogens in the Prevention of Prostate Cancer: In vivo Evidences from Murine Models and Human Clinical Studies
R Lattanzio, A Lamolinara, M Piantelli… - Advances in Prostate …, 2013 - books.google.com
Prostate cancer (PCa) is the most frequent malignant neoplasia in men. The number of
cases has continuously increased over the past decades, partly due to the higher life …
cases has continuously increased over the past decades, partly due to the higher life …