Maternal-offspring interactions in mammals involve both cooperation and conflict. The fetus
has evolved ways to manipulate maternal physiology to enhance placental nutrient transfer …

Simple Summary Congenital lateralized or segmental overgrowth (LO) disorders are
conditions characterized by excessive tissue growth of a body region often associated with a …

Beckwith‐Wiedemann syndrome (BWS) is the most common epigenetic overgrowth and
cancer predisposition disorder. Due to both varying molecular defects involving …

Abstract Background Beckwith-Wiedemann syndrome (BWS) is a cancer predisposition
syndrome caused by defects on chromosome 11p15. 5. The quantitative cancer risks in …

One-carbon (1-C) metabolic deficiency impairs homeostasis, driving disease development,
including infertility. It is of importance to summarize the current evidence regarding the …

Simple Summary Beckwith–Wiedemann Spectrum (BWSp) is a disorder predisposing to
tumors of embryonic origin arising during childhood. Little is known concerning tumor risk …

Beckwith–Wiedemann syndrome (BWS) is a congenital overgrowth disorder caused by
various (epi) genetic alterations affecting the expression of genes on chromosome 11p15 …

Abstract The prevalence of Beckwith–Wiedemann spectrum (BWSp) is tenfold increased in
children conceived through assisted reproductive techniques (ART). More than 90% of ART …

Due to associated maxillofacial growth anomalies and the impairment of oral functions,
macroglossia may negatively impact the oral health-related quality of life (OHRQoL) of …

Background Most cases of Beckwith-Wiedemann spectrum (BWSp) are diagnosed after birth
and few studies evaluated the prenatal phenotype; here, we investigate these aspects in a …