Abstract MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif)
ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of …

Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …

Functional and nutraceutical foods provide an alternative way to improve immune function to
aid in the management of various diseases. Traditionally, many medicinal products have …

Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …

Tryptophan (TRP), an essential amino acid in mammals, is involved in several physiological
processes including neuronal function, immunity, and gut homeostasis. In humans, TRP is …

AIM2 is a cytosolic innate immune receptor which recognizes double‐stranded DNA
(dsDNA) released during cellular perturbation and pathogenic assault. AIM2 recognition of …

The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

Epidemiological studies have demonstrated that nutritional habits, like those based on high
consumption of fruits and vegetables, have been associated with a longer life expectancy …

The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated
through both adaptive and innate immunity has led to the hypothesis that anticytokine …