[HTML][HTML] Oxidative stress, inflammation, gut dysbiosis: what can polyphenols do in inflammatory bowel disease?

L Li, P Peng, N Ding, W Jia, C Huang, Y Tang - Antioxidants, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a long-term, progressive, and recurrent intestinal
inflammatory disorder. The pathogenic mechanisms of IBD are multifaceted and associated …

[HTML][HTML] Nrf2: A Main Responsive Element of the Toxicity Effect Caused by Trichothecene (T-2) Mycotoxin

Y Wang, Y Liu, T Huang, Y Chen, W Song, F Chen… - Toxics, 2023 - mdpi.com
T-2 toxin, the most toxic type A trichothecene mycotoxin, is produced by Fusarium, and is
widely found in contaminated feed and stored grains. T-2 toxin is physicochemically stable …

[HTML][HTML] Pictolysin-III, a Hemorrhagic Type-III Metalloproteinase Isolated from Bothrops pictus (Serpentes: Viperidae) Venom, Reduces Mitochondrial Respiration and …

DE Vivas-Ruiz, P Rosas, A Proleón, D Torrejón, F Lazo… - Pharmaceutics, 2023 - mdpi.com
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently
have described toxins that inhibited platelet aggregation and cancer cell migration. In this …

[HTML][HTML] Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

G Pratelli, B Tamburini, D Carlisi, A De Blasio… - International Journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and progressive inflammatory disorder
affecting the gastrointestinal tract (GT) caused by a wide range of genetic, microbial, and …

[HTML][HTML] Mitochondrial quality control in human health and disease

BH Liu, CZ Xu, Y Liu, ZL Lu, TL Fu, GR Li… - Military Medical …, 2024 - Springer
Mitochondria, the most crucial energy-generating organelles in eukaryotic cells, play a
pivotal role in regulating energy metabolism. However, their significance extends beyond …

Intestinal microflora promotes Th2-mediated immunity through NLRP3 in damp and heat environments

Y Luo, X Huang, H Hu, Y Wang, X Feng… - Frontiers in …, 2024 - frontiersin.org
Background With the worsening of the greenhouse effect, the correlation between the damp-
heat environment (DH) and the incidence of various diseases has gained increasing …

Cholesterol uptake in the intestine is regulated by the LASP1-AKT-NPC1L1 signaling pathway

E Butt, T Guender, P Stuerzebecher… - American Journal …, 2024 - journals.physiology.org
Cholesterol is essential for the stability and architecture of the plasma membrane and a
precursor of bile acids and steroid hormones in mammals. Excess dietary cholesterol uptake …

Inhibition of Pck1 in intestinal epithelial cells alleviates acute pancreatitis via modulating intestinal homeostasis

N Yin, B Xu, Z Huang, Y Fu, H Huang, J Fan… - The FASEB …, 2024 - Wiley Online Library
Intestinal barrier dysfunction usually occurred in acute pancreatitis (AP) but the mechanism
remains unclear. In this study, RNA sequencing of ileum in L‐arginine‐induced AP mice …

Drp1: Focus on Diseases Triggered by the Mitochondrial Pathway

F Sun, M Fang, H Zhang, Q Song, S Li, Y Li… - Cell Biochemistry and …, 2024 - Springer
Abstract Drp1 (Dynamin-Related Protein 1) is a cytoplasmic GTPase protein encoded by the
DNM1L gene that influences mitochondrial dynamics by mediating mitochondrial fission …

[HTML][HTML] Link between mutations in ACVRL1 and PLA2G4A genes and chronic intestinal ulcers: A case report and review of literature

YJ Tang, J Zhang, J Wang, RD Tian… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Genetic factors of chronic intestinal ulcers are increasingly garnering
attention. We present a case of chronic intestinal ulcers and bleeding associated with …