Given the global burden of heart failure, strategies to understand the underlying cause or to
provide prognostic information are critical to reducing the morbidity and mortality associated …

Left ventricular hypertrabeculation (LVHT) or noncompaction is a myocardial abnormality of
unknown aetiology, frequently associated with monogenic disorders, particularly …

Left ventricular noncompaction (LVNC) causes prominent ventricular trabeculations and
reduces cardiac systolic function. The clinical presentation of LVNC ranges from …

Mitochondria are found in all nucleated human cells and perform various essential functions,
including the generation of cellular energy. Mitochondria are under dual genome control …

Mitochondrial disease is a heterogeneous group of multisystemic diseases that develop
consequent to mutations in nuclear or mitochondrial DNA. The prevalence of inherited …

Ischemic heart disease is a significant cause of morbidity and mortality in Western society.
Although interventions, such as thrombolysis and percutaneous coronary intervention, have …

Mitochondrial disease refers to a heterogenous group of genetic disorders that result from
dysfunction of the final common pathway of energy metabolism. Mitochondrial DNA …

Inherited cardiomyopathies include hypertrophic cardiomyopathy, dilated cardiomyopathy,
arrhythmogenic right ventricular cardiomyopathy, left ventricular noncompaction, and …

Background Left ventricular noncompaction (LVNC) is a distinct form of cardiomyopathy
characterized by hypertrabeculation of the left ventricle. The LVNC phenotype may occur in …

Background: Left ventricular noncompaction (LVNC) is the third most common pediatric
cardiomyopathy characterized by a thinned myocardium and prominent trabeculations. Next …