Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds

HL Ang, CD Mohan, MK Shanmugam… - Medicinal research …, 2023 - Wiley Online Library
Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

Optimization and modeling of microwave-assisted extraction of curcumin and antioxidant compounds from turmeric by using natural deep eutectic solvents

K Doldolova, M Bener, M Lalikoğlu, YS Aşçı, R Arat… - Food Chemistry, 2021 - Elsevier
Natural deep eutectic solvents (NADES) have recently come to the fore as new green
solvents for foods, cosmetics and pharmaceuticals due to their unique solvation power and …

[HTML][HTML] Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

Chitosan-alginate nanoparticles as effective oral carriers to improve the stability, bioavailability, and cytotoxicity of curcumin diethyl disuccinate

FN Sorasitthiyanukarn, C Muangnoi, P Rojsitthisak… - Carbohydrate …, 2021 - Elsevier
Curcumin diethyl disuccinate (CDD) is an ester prodrug of curcumin that has better chemical
stability in phosphate buffer (pH 7.4) and anticancer activities against MDA-MB-231 human …

Potential therapeutic effects of curcumin mediated by JAK/STAT signaling pathway: a review

M Ashrafizadeh, H Rafiei… - Phytotherapy …, 2020 - Wiley Online Library
Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …

Polyphenols: Natural compounds with promising potential in treating polycystic ovary syndrome

A Mihanfar, M Nouri, L Roshangar… - Reproductive …, 2021 - Elsevier
Polyphenols are natural compounds used by plants as a defense system against various
stresses. In recent years, the importance of these polyhydroxyphenols has extensively …

The combinatory effects of natural products and chemotherapy drugs and their mechanisms in breast cancer treatment

Y Zhang, H Li, J Zhang, C Zhao, S Lu, J Qiao… - Phytochemistry …, 2020 - Springer
Breast cancer is the leading cause of cancer-related death among females. The global
morbidity and mortality associated with breast cancer have recently been increasing …

The effect of oral capsule of curcumin and vitamin E on the hot flashes and anxiety in postmenopausal women: A triple blind randomised controlled trial

K Ataei-Almanghadim, A Farshbaf-Khalili… - … therapies in medicine, 2020 - Elsevier
Objective The decline and eventual cessation of estrogen production cause a variety of
symptoms during menopause, affecting each woman differently. Most women reported …

Diffusion Modeling and in vitro release kinetics studies of curcumin− loaded superparamagnetic nanomicelles in cancer drug delivery system

T Santadkha, W Skolpap, V Thitapakorn - Journal of Pharmaceutical …, 2022 - Elsevier
The purpose of this study was to investigate in vitro drug release kinetics and to develop
diffusion model of curcumin loaded Pluronic F127/Oleic acid (OA)-Fe 3 O 4 nanoparticles …