[HTML][HTML] Measles virus infection and immunity in a suboptimal vaccination coverage setting

M Pacenti, N Maione, E Lavezzo, E Franchin… - Vaccines, 2019 - mdpi.com
Despite efforts to improve surveillance and vaccination coverage, measles virus (MeV)
continues to cause outbreaks also in high-income countries. As the reference laboratory of …

[HTML][HTML] Loss of STAT2 may be dangerous in a world filled with viruses

MB Jordan - The Journal of Clinical Investigation, 2023 - Am Soc Clin Investig
Type I IFNs, a family of cytokines that signal through a single receptor and signaling
mechanism, were originally named for their ability to interfere with viral replication. While …

Human genetic and immunological determinants of SARS‐CoV‐2 and Epstein–Barr virus diseases in childhood: Insightful contrasts

Q Pan‐Hammarström… - Journal of Internal …, 2023 - Wiley Online Library
There is growing evidence to suggest that severe disease in children infected with common
viruses that are typically benign in other children can result from inborn errors of immunity or …

[HTML][HTML] Biodistribution and environmental safety of a live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate

LH Li, L Liesenborghs, L Wang, M Lox… - … Therapy-Methods & …, 2022 - cell.com
New platforms are needed for the design of novel prophylactic vaccines and advanced
immune therapies. Live-attenuated yellow fever vaccine YF17D serves as a vector for …

Nucleotide metabolism, leukodystrophies, and CNS pathology

F Gavazzi, CD Gonzalez, K Arnold… - Journal of Inherited …, 2024 - Wiley Online Library
The balance between a protective and a destructive immune response can be precarious,
as exemplified by inborn errors in nucleotide metabolism. This class of inherited disorders …

Empfehlungen der Ständigen Impfkommission (STIKO) und der Deutschen Gesellschaft für Tropenmedizin, Reisemedizin und Globale Gesundheit eV (DTG) zu …

K Kling, W Külper-Schiek, C Rothe, G Boecken… - 2024 - edoc.rki.de
Die STIKO empfiehlt Reiseimpfungen zum individuellen Schutz Reisender mit einem
Expositionsrisiko gegenüber bestimmten impfpräventablen Erkrankungen und um den …

Anti-cytokine autoantibodies and inborn errors of immunity

AAS Akha, A Kumánovics - Journal of Immunological Methods, 2022 - Elsevier
The past quarter of a century has witnessed an inordinate increase in our understanding of
primary immunodeficiencies/inborn errors of immunity. These include a significant increase …

New immunodeficiency syndromes that help us understand the IFN-mediated antiviral immune response

H Jing, HC Su - Current opinion in pediatrics, 2019 - journals.lww.com
New immunodeficiency syndromes that help us understand the I... : Current Opinion in
Pediatrics New immunodeficiency syndromes that help us understand the IFN-mediated …

[HTML][HTML] Human genetic basis of fulminant viral hepatitis

E Jouanguy - Human Genetics, 2020 - Springer
In rare cases, hepatitis A virus (HAV) and hepatitis B virus (HBV) can cause fulminant viral
hepatitis (FVH), characterized by massive hepatocyte necrosis and an inflammatory infiltrate …

[HTML][HTML] Participation of Single-Nucleotide Variants in IFNAR1 and IFNAR2 in the Immune Response against SARS-CoV-2 Infection: A Systematic Review

MF López-Bielma, R Falfán-Valencia, E Abarca-Rojano… - Pathogens, 2023 - mdpi.com
Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …