The application of evolutionary and ecological principles to cancer prevention and
treatment, as well as recognizing cancer as a selection force in nature, has gained impetus …

Cancer has deep evolutionary roots and is an important source of selective pressure in
organismal evolution. Yet, we find a great deal of variation in cancer vulnerabilities across …

Immune system has evolved to maintain homeostatic balance between effector and
regulatory immunity, which is critical to both elicit an adequate protective response to fight …

Reproduction is a central activity for all living organisms but is also associated with a
diversity of costs that are detrimental for survival. Until recently, the cost of cancer as a …

Growing evidence indicates that human activities are causing cancer rates to rise in both
human and wildlife populations. This is due to the inability of ancestral anti‐cancer defences …

Cancer is a family of diseases that has been documented in most metazoan species and
ecosystems. Human induced environmental changes are increasingly exposing wildlife to …

Cancer, a disease due to uncontrolled cell proliferation is as ancient as multicellular
organisms. A 255-million-years-old fossilized forerunner mammal gorgonopsian is probably …

Reproduction is one of the most energetically demanding life-history stages. As a result,
breeding individuals often experience trade-offs, where energy is diverted away from …

In some species, permanent curtailment of reproduction part‐way through the lifespan of
adult females is a feature of their evolved life history. The existence of such a post …

Cellular cheating leading to cancers exists in all branches of multicellular life, favoring the
evolution of adaptations to avoid or suppress malignant progression, and/or to alleviate its …