Cancer metabolites: promising biomarkers for cancer liquid biopsy

W Wang, Z Rong, G Wang, Y Hou, F Yang, M Qiu - Biomarker Research, 2023 - Springer
Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular
metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of …

Quantitative NMR spectroscopy of complex mixtures

P Giraudeau - Chemical Communications, 2023 - pubs.rsc.org
Complex mixtures are ubiquitous in many branches of chemistry, be it a complex
pharmaceutical formulation, a collection of biofluids analysed in a metabolomics workflow …

NMR methods for the analysis of mixtures

JN Dumez - Chemical Communications, 2022 - pubs.rsc.org
NMR spectroscopy is a powerful approach for the analysis of mixtures. Its usefulness arises
in large part from the vast landscape of methods, and corresponding pulse sequences, that …

Paramagnetic relaxation agents for enhancing temporal resolution and sensitivity in multinuclear FlowNMR spectroscopy

A Bara‐Estaún, MC Harder, CL Lyall… - … A European Journal, 2023 - Wiley Online Library
Sensitivity in FlowNMR spectroscopy for reaction monitoring often suffers from low levels of
pre‐magnetisation due to limited residence times of the sample in the magnetic field. While …

Absolute Metabolite Quantification Using Pure Shift NMR: Toward Quantitative Metabolic Profiling of Aqueous Biological Samples

X Chen, C Caradeuc, A Montagne, V Baud… - Analytical …, 2022 - ACS Publications
Accurate quantification of metabolites by nuclear magnetic resonance (NMR) is of prime
importance in the field of health sciences for understanding the metabolic pathways of the …

Solution‐State 2D NMR Spectroscopy of Mixtures HyperpolarizedUsing Optically Polarized Crystals

AJ Parker, A Dey, M Usman Qureshi… - Angewandte …, 2023 - Wiley Online Library
Abstract The HYPNOESYS method (Hyperpolarized NOE System), which relies on the
dissolution of optically polarized crystals, has recently emerged as a promising approach to …

Benchtop NMR-Based Metabolomics: First Steps for Biomedical Application

P Alonso-Moreno, I Rodriguez, JL Izquierdo-Garcia - Metabolites, 2023 - mdpi.com
Nuclear magnetic resonance (NMR)-based metabolomics is a valuable tool for identifying
biomarkers and understanding the underlying metabolic changes associated with various …

[HTML][HTML] Glutamine: A key player in human metabolism as revealed by hyperpolarized magnetic resonance

K Dos Santos, G Bertho, M Baudin, N Giraud - Progress in Nuclear …, 2024 - Elsevier
In recent years, there has been remarkable progress in the field of dissolution dynamic
nuclear polarization (D-DNP). This method has shown significant potential for enhancing …

In‐line Multidimensional NMR Monitoring of Photochemical Flow Reactions

M Bazzoni, C Lhoste, J Bonnet… - … A European Journal, 2023 - Wiley Online Library
This work demonstrates the in‐line monitoring of a flow photochemical reaction using 1D
and ultrafast 2D NMR methods at high magnetic field. The reaction mixture exiting the flow …

Recent developments in the use of nanocrystals to improve bioavailability of APIs

Y Ding, T Zhao, J Fang, J Song, H Dong… - Wiley …, 2024 - Wiley Online Library
Nanocrystals refer to materials with at least one dimension smaller than 100 nm, composing
of atoms arranged in single crystals or polycrystals. Nanocrystals have significant research …