Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

The review of alpha‐linolenic acid: Sources, metabolism, and pharmacology

Q Yuan, F Xie, W Huang, M Hu, Q Yan… - Phytotherapy …, 2022 - Wiley Online Library
α‐linolenic acid (ALA, 18: 3n‐3) is a carboxylic acid composed of 18 carbon atoms and three
cis double bonds, and is an essential fatty acid indispensable to the human body. This study …

The role of glial autophagy in Alzheimer's disease

A Litwiniuk, GR Juszczak, AM Stankiewicz… - Molecular …, 2023 - nature.com
Although Alzheimer's disease is the most pervasive neurodegenerative disorder, the
mechanism underlying its development is still not precisely understood. Available data …

[HTML][HTML] Unsaturated fatty acids and their immunomodulatory properties

S Coniglio, M Shumskaya, E Vassiliou - Biology, 2023 - mdpi.com
Simple Summary Diet can influence human health in both positive and negative ways. Ω-3
polyunsaturated fatty acids have an overall positive effect on humans. The sources of these …

[HTML][HTML] Exosomes derived from M2 microglia cells attenuates neuronal impairment and mitochondrial dysfunction in Alzheimer's disease through the PINK1/Parkin …

N Li, J Shu, X Yang, W Wei, A Yan - Frontiers in Cellular …, 2022 - frontiersin.org
The accumulation of abnormal aggregation of amyloid-β plaques is one of the most
distinguishing pathologies of Alzheimer's disease (AD) and is highly toxic to neurons …

[HTML][HTML] Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia

OY Kim, J Song - Life Sciences, 2023 - Elsevier
Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

[HTML][HTML] Inflammasome NLRP3 potentially links obesity-associated low-grade systemic inflammation and insulin resistance with Alzheimer's disease

A Litwiniuk, W Bik, M Kalisz… - International Journal of …, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia.
Metabolic disorders including obesity and type 2 diabetes mellitus (T2DM) may stimulate …

Association of Alzheimer's dementia with oral bacteria, vitamin B12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics …

P Prajjwal, S Asharaf, D Makhanasa, A Yamparala… - Disease-a-Month, 2023 - Elsevier
Alzheimer's disease is a prevalent form of dementia, particularly among the elderly
population. It is characterized by progressive cognitive decline and neurodegeneration …

Baicalin Attenuated Aβ1-42‐Induced Apoptosis in SH‐SY5Y Cells by Inhibiting the Ras‐ERK Signaling Pathway

Z Song, C He, W Yu, M Yang, Z Li, P Li… - BioMed Research …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a serious neurodegenerative disease. It is widely believed that
the accumulation of amyloid beta (Aβ) in neurons around neurofibrillary plaques is the main …

[HTML][HTML] Sodium Humate Alleviates Enterotoxigenic Escherichia coli-Induced Intestinal Dysfunction via Alteration of Intestinal Microbiota and Metabolites in Mice

D Wang, Y He, K Liu, S Deng, Y Fan, Y Liu - Frontiers in Microbiology, 2022 - frontiersin.org
Enterotoxigenic Escherichia coli (ETEC) can damage intestinal epithelial barrier function
and lead to serious intestinal diarrhea in newborns and young animals. Sodium humate …