The neuroimmune mechanism underlying neuropathic pain has been extensively studied.
Tumor necrosis factor-alpha (TNF-α), a key pro-inflammatory cytokine that drives cytokine …

Emerging clinical and experimental evidence demonstrates that neuroinflammation plays an
important role in cognitive impairment associated with neuropathic pain. However, how …

Economic growth has lifted billions out of poverty in the span of a few generations. Despite
these positive trends, poverty remains entrenched for millions around the globe. One long …

Acutely, pain is protective. It promotes escape from, and future avoidance of, noxious stimuli
through strong and often lifetime associative memories. However, with persistent acute pain …

Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …

Background. Pain related to many age-related chronic conditions is a burdensome problem
in elderly adults and may also interfere with cognitive functioning. The purpose of this study …

Chronic pain is characterised by an ongoing and fluctuating intensity over time. Here, we
investigated how the trajectory of the patients' endogenous pain is encoded in the brain. In …

Pain sensation is essential for survival, since it draws attention to physical threat to the body.
Pain assessment is usually done through self-reports. However, self-assessment of pain is …

Considerable interest has arisen concerning the relationship between hereditary connective
tissue disorders such as the Ehlers-Danlos syndromes (EDS)/hypermobility spectrum …

A growing body of empirical research has confirmed an association between chronic pain
and cognitive dysfunction. The aim of the present study was to determine whether cognitive …