Recent successes in heart failure treatment

CSP Lam, KF Docherty, JE Ho, JJV McMurray… - Nature Medicine, 2023 - nature.com
Remarkable recent advances have revolutionized the field of heart failure. Survival has
improved among individuals with heart failure and a reduced ejection fraction and for the …

[HTML][HTML] Heart failure with preserved ejection fraction: The pathophysiological mechanisms behind the clinical phenotypes and the therapeutic approach

L Stoicescu, D Crişan, C Morgovan, L Avram… - International Journal of …, 2024 - mdpi.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is an increasingly frequent form
and is estimated to be the dominant form of HF. On the other hand, HFpEF is a syndrome …

Heart failure with preserved ejection fraction: everything the clinician needs to know

P Campbell, FH Rutten, MMY Lee, NM Hawkins… - The Lancet, 2024 - thelancet.com
Heart failure with preserved ejection fraction (HFpEF) is increasingly recognised and
diagnosed in clinical practice, a trend driven by an ageing population and a rise in …

Cardiovascular‐kidney‐metabolic overlap in heart failure with preserved ejection fraction: Cardiac structure and function, clinical outcomes, and response to sacubitril …

MCH Lassen, JW Ostrominski… - European Journal of …, 2024 - Wiley Online Library
Aims Cardiovascular‐kidney‐metabolic (CKM) multimorbidity is prevalent among individuals
with heart failure (HF), but whether cardiac structure and function, clinical outcomes, and …

Contemporary American and European Guidelines for Heart Failure Management: JACC: Heart Failure Guideline Comparison

JW Ostrominski, EM DeFilippis, K Bansal, RJ Riello III… - Heart Failure, 2024 - jacc.org
This review serves to compare contemporary clinical practice recommendations for the
management of heart failure (HF), as codified in the 2021 European Society of Cardiology …

[HTML][HTML] Latest pharmaceutical approaches across the spectrum of heart failure

D Bismpos, J Wintrich, J Hövelmann, M Böhm - Heart Failure Reviews, 2024 - Springer
Despite major advances in prevention and medical therapy, heart failure (HF) remains
associated with high morbidity and mortality, especially in older and frailer patients …

Sodium–glucose co-transporter 2 inhibitors and mineralocorticoid receptor antagonists synergism in heart failure: it takes two to tango

J Bauersachs, S Soltani - European Heart Journal, 2023 - academic.oup.com
Synergistic effects of MRA and SGLT2i in HF: Key beneficial effects (+) of mineralocorticoid
receptor antagonists (MRA) and sodium–glucose co-transporter inhibitors (SGLT2i) on …

Advances in management of heart failure

P Heidenreich, A Sandhu - bmj, 2024 - bmj.com
Heart failure is increasing in prevalence in many countries with aging populations.
Fortunately, remarkable scientific advances have been made in the past few years that have …

2024 update in heart failure

A Beghini, AM Sammartino, Z Papp… - ESC Heart …, 2024 - Wiley Online Library
In the last years, major progress has occurred in heart failure (HF) management. The 2023
ESC focused update of the 2021 HF guidelines introduced new key recommendations …

[HTML][HTML] Cost-effectiveness of medical therapy for heart failure with mildly reduced and preserved ejection fraction

NM Dixit, KP Truong, M Vaduganathan, B Ziaeian… - JACC: Heart Failure, 2024 - Elsevier
Background Three medications are now guideline-recommended treatments for heart failure
with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), however, the cost …