The current carbapenem-resistant gram-negative bacteria (CR-GN) treatment guidelines
lack strong evidence about cefiderocol (CFD) efficacy against CR-GN, especially CRAB. The …

Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) infections are
associated with high mortality rates. The optimal treatment regimen for CRAB has not been …

Background Antimicrobial resistance represents a major critical issue for the management of
the critically ill patients hospitalized in the intensive care unit (ICU), since infections by …

Antimicrobial photodynamic therapy (aPDT) is a method that does not seem to promote
antimicrobial resistance. Photosensitizers (PS) conjugated with inorganic nanoparticles for …

We reviewed the literature of last 20 years and found a limited number of studies evaluating
the relationship between heteroresistance and clinical outcome in nonfermenting GNB …

Objectives Little is known regarding outcomes and optimal therapeutic regimens of
infections caused by Klebsiella pneumoniae carbapenemase-producing Klebsiella …

Clinical diagnostic laboratories produce one product—information—and for this to be
valuable, the information must be clinically relevant, accurate, and timely. Although …

Purpose Real-world experience with meropenem/vaborbactam (M/V) is limited. Our aim is to
report a clinical experience of M/V in the treatment of resistant Gram-negative bacilli …

Carbapenem-resistant Acinetobacter baumannii (CRAB), an important opportunistic
pathogen, is a major cause of healthcare-associated infections. The polymyxins (colistin and …

The use of rapid molecular tests may anticipate the identification of causative agents and
resistance determinants in the blood of critically ill patients with sepsis. From April to …