The global cognitive impairment in schizophrenia: consistent over decades and around the world

J Schaefer, E Giangrande, DR Weinberger… - Schizophrenia …, 2013 - Elsevier
Objective Schizophrenia results in cognitive impairments as well as positive, negative, and
disorganized symptomatology. The present study examines the extent to which these …

Model-based cognitive neuroscience approaches to computational psychiatry: clustering and classification

TV Wiecki, J Poland, MJ Frank - Clinical Psychological …, 2015 - journals.sagepub.com
Psychiatric research is in crisis. We highlight efforts to overcome current challenges by
focusing on the emerging field of computational psychiatry, which might enable the field to …

Response inhibition and psychopathology: a meta-analysis of go/no-go task performance.

L Wright, J Lipszyc, A Dupuis… - Journal of abnormal …, 2014 - psycnet.apa.org
Response inhibition, defined as the ability to withhold a response, is considered to be a core
deficit in various mental illnesses. Measures of response inhibition have been used to define …

Inhibitory control and psychopathology: a meta-analysis of studies using the stop signal task

J Lipszyc, R Schachar - Journal of the International …, 2010 - cambridge.org
The Stop Signal Task (SST) is a measure that has been used widely to assess response
inhibition. We conducted a meta-analysis of studies that examined SST performance in …

A computational model of inhibitory control in frontal cortex and basal ganglia.

TV Wiecki, MJ Frank - Psychological review, 2013 - psycnet.apa.org
Planning and executing volitional actions in the face of conflicting habitual responses is a
critical aspect of human behavior. At the core of the interplay between these 2 control …

Functional connectivity delineates distinct roles of the inferior frontal cortex and presupplementary motor area in stop signal inhibition

JR Duann, JS Ide, X Luo, CR Li - Journal of Neuroscience, 2009 - Soc Neuroscience
The neural basis of motor response inhibition has drawn considerable attention in recent
imaging literature. Many studies have used the go/no-go or stop signal task to examine the …

[HTML][HTML] Clarifying inhibitory control: Diversity and development of attentional inhibition

SJ Howard, J Johnson, J Pascual-Leone - Cognitive Development, 2014 - Elsevier
Attentional inhibition is the ability to suppress task-irrelevant cognitive processing and
ignore salient yet irrelevant features of the situation. However, it remains unclear whether …

Assessing cognitive function in clinical trials of schizophrenia

JH Barnett, TW Robbins, VC Leeson… - Neuroscience & …, 2010 - Elsevier
Cognitive dysfunction in schizophrenia is an important target for novel therapies. Effectively
measuring the cognitive effects of compounds in clinical trials of schizophrenia could be a …

Reduced proactive inhibition in schizophrenia is related to corticostriatal dysfunction and poor working memory

BB Zandbelt, M van Buuren, RS Kahn, M Vink - Biological psychiatry, 2011 - Elsevier
BACKGROUND: Inhibitory control is central to executive functioning and appears deficient in
schizophrenia. However, it is unclear how inhibitory control is affected, what the underlying …

Disruption of conscious access in psychosis is associated with altered structural brain connectivity

L Berkovitch, L Charles, A Del Cul… - Journal of …, 2021 - Soc Neuroscience
According to global neuronal workspace (GNW) theory, conscious access relies on long-
distance cerebral connectivity to allow a global neuronal ignition coding for conscious …