Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation
affecting predominantly the lung parenchyma and peripheral airways that results in largely …

Asthma and chronic obstructive pulmonary disease (COPD) both cause airway obstruction
and are associated with chronic inflammation of the airways. However, the nature and sites …

Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …

Cytokines play a key role in orchestrating and perpetuating the chronic airway inflammation
in asthma and chronic obstructive pulmonary disease (COPD), making them attractive …

COPD is characterized by chronic bronchitis, chronic airway obstruction, and emphysema,
leading to a progressive and irreversible decline in lung function. Inflammation is central for …

Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

Innate lymphoid cells (ILCs) are innate counterparts of T cells that contribute to immune
responses by secreting effector cytokines and regulating the functions of other innate and …

Early-Life Origins of Chronic Obstructive Pulmonary Disease | New England Journal of Medicine
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Transcription factor nuclear factor erythroid 2‐related factor 2 (Nrf2) is a major regulator of
antioxidant response element‐(ARE‐) driven cytoprotective protein expression. The …

Cigarette smoke is a representative source of toxic chemical exposures to humans, and the
adverse consequences of cigarette smoking are mediated by its effect on both neuronal and …