Islet transplantation (IT) is now a robust treatment for selected patients with type 1 diabetes
suffering from recurrent hypoglycemia and impaired awareness of hypoglycemia. A global …

Transplantation (CIT) Consortium jointly developed and implemented a harmonized process
for manufacture of the allogeneic Purified Human Pancreatic Islet (PHPI) product evaluated …

The utilisation of bioartificial organs is of significant interest to many due to their versatility in
treating a wide range of disorders. Microencapsulation has a potentially significant role in …

Eight manufacturing facilities participating in the National Institutes of Health–sponsored
Clinical Islet Transplantation (CIT) Consortium jointly developed and implemented a …

Collagens are the most abundant fibrous protein in the human body and constitute the main
structural element of the extracellular matrix. It provides mechanical and physiological …

Background. Islet transplantation is a promising option for the treatment of type 1 diabetes.
However, the current lack of practical techniques for the isolated islets preservation still …

Islet transplantation offers improved glycemic control in individuals with type 1 diabetes
mellitus. However, in vitro islet culture is associated with islet apoptosis and eventually will …

Investigation of the neutralizing behavior of concrete is essential, as it can help reveal the
durability properties of concrete structures. In this paper, anthocyanin extracted from …

Islet culture before clinical transplantation has been adopted by various centers, but its effect
on the survival and function of islets relative to the culture conditions and media needs …

The ability to routinely and reproducibly obtain purified human islets has facilitated
substantial progress in providing a safe and reliable treatment option for adult patients of …