[HTML][HTML] Combined small cell lung cancer: current progress and unmet needs

C Zeng, G Qiu, X Xie, T Liu, Z Chen… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Combined small cell lung cancer (CSCLC) is a specific subtype of lung cancer characterized
by a pathological mixture of small cell lung cancer and any subtype of non-small cell lung …

Whole-process treatment of combined small cell lung cancer initially diagnosed as “lung squamous cell carcinoma”: a case report and review of the literature

Y Dong, Q Li, D Li, Y Fang, C Wang - Frontiers in immunology, 2022 - frontiersin.org
The rarity and complexity of histology lead to the low diagnosis rate and high misdiagnosis
rate of combined small cell lung cancer (C-SCLC). Nowadays, C-SCLC has no commonly …

[HTML][HTML] YAP1 protein expression has variant prognostic significance in small cell lung cancer (SCLC) stratified by histological subtypes

X Wang, Y Guo, L Liu, J Wei, J Zhang, T Xie, J Dong… - Lung Cancer, 2021 - Elsevier
Background Recently, expression of YAP1, a nuclear effector of an inactivated HIPPO
pathway, has been identified as one of four molecular subtypes of SCLC. However, the …

ASCL1 and DLL3 expressions and their clinicopathological implications in surgically resected pure small cell lung cancer: A study of 247 cases from the National …

C Hu, J Dong, L Liu, J Liu, X Sun, F Teng… - Thoracic …, 2022 - Wiley Online Library
Objective Small cell lung cancer (SCLC) is one of the most aggressive malignancies
characterized by neuroendocrine (NE) differentiation. The Delta‐like protein 3 (DLL3), as a …

Clinicopathological and treatment patterns of combined small-cell lung carcinoma with future insight to treatment: a population-based study

A Ullah, O Saeed, NR Karki, M Goodbee… - Journal of clinical …, 2023 - mdpi.com
Background: Primary lung cancer is the most common cause of cancer-related mortality in
the United States (US). Approximately 90% of lung cancers are associated with smoking and …

Design and evaluation of sulfadiazine derivatives as potent dual inhibitors of EGFR WT and EGFR T790M: integrating biological, molecular docking, and ADMET …

HM Abd El-Lateef, HAA Ezelarab, AM Ali, AT Alsaggaf… - RSC …, 2024 - pubs.rsc.org
A series of derivatives (5–14) were synthesized through the diazotization of sulfadiazine with
active methylene compounds. The chemical structures of these newly designed compounds …

[HTML][HTML] Clinicopathological features and prognostic analysis of 247 small cell lung cancer with limited-stage after surgery

L Liu, J Wei, F Teng, Y Zhu, P Xing, J Zhang, Y Guo… - Human Pathology, 2021 - Elsevier
The objective of this study was to analyze the clinical and pathological characteristics of
patients with small cell lung cancer (SCLC) after curative surgery and to explore prognostic …

Different clinical characteristics and survival between surgically resected pure and combined small cell lung cancer

Y Li, Y Wang, W Zhou, Y Chen, Y Lou, F Qian… - Thoracic …, 2022 - Wiley Online Library
Background Small cell lung cancer (SCLC) is the most malignant and common form of
neuroendocrine lung cancer with pure (P‐SCLC) and combined subtypes (C‐SCLC) …

Exploring the molecular features and genetic prognostic factors of pulmonary high-grade neuroendocrine carcinomas

H Wang, L Yan, Y Zhu, W Sun, X Yang, X Liu, K Chi… - Human Pathology, 2023 - Elsevier
Molecular research on large-cell neuroendocrine carcinoma (LCNEC) and small-cell lung
cancer (SCLC) has progressed significantly. However, there are still fewer molecular …

Construction and validation of a novel nomogram to predict the overall survival of patients with combined small cell lung cancer: A surveillance, epidemiology, and …

A Jiang, N Liu, R Zhao, S Liu, H Gao, J Wang… - Cancer …, 2021 - journals.sagepub.com
Introduction Combined small cell lung cancer (C-SCLC) represents a rare subtype of all
small cell lung cancer cases, with limited studies investigated its prognostic factors. The aim …