Head and neck cancer: improving outcomes with a multidisciplinary approach
C Lo Nigro, N Denaro, A Merlotti… - Cancer management and …, 2017 - Taylor & Francis
For early-stage head and neck cancer (HNC), surgery (S) or radiotherapy (RT) is a standard
treatment. The multidisciplinary approach, which includes multimodality treatment with S …
treatment. The multidisciplinary approach, which includes multimodality treatment with S …
Precision medicine in head and neck cancer
Head and Neck cancer is among the most common cancers worldwide, with a high
prevalence in south East Asia, Brazil and central Europe. Head and Neck Squamous cell …
prevalence in south East Asia, Brazil and central Europe. Head and Neck Squamous cell …
[HTML][HTML] Machine learning identifies stemness features associated with oncogenic dedifferentiation
Cancer progression involves the gradual loss of a differentiated phenotype and acquisition
of progenitor and stem-cell-like features. Here, we provide novel stemness indices for …
of progenitor and stem-cell-like features. Here, we provide novel stemness indices for …
Oral mucosal organoids as a potential platform for personalized cancer therapy
E Driehuis, S Kolders, S Spelier, K Lõhmussaar… - Cancer discovery, 2019 - AACR
Previous studies have described that tumor organoids can capture the diversity of defined
human carcinoma types. Here, we describe conditions for long-term culture of human …
human carcinoma types. Here, we describe conditions for long-term culture of human …
An immunogenic cell death-related classification predicts prognosis and response to immunotherapy in head and neck squamous cell carcinoma
X Wang, S Wu, F Liu, D Ke, X Wang, D Pan… - Frontiers in …, 2021 - frontiersin.org
Immunogenic cell death (ICD) has been classified as a form of regulated cell death (RCD)
that is sufficient to activate an adaptive immune response. Accumulating evidence has …
that is sufficient to activate an adaptive immune response. Accumulating evidence has …
Immunotherapy targeting HPV16/18 generates potent immune responses in HPV-associated head and neck cancer
C Aggarwal, RB Cohen, MP Morrow, KA Kraynyak… - Clinical Cancer …, 2019 - AACR
Purpose: Clinical responses with programmed death (PD-1) receptor–directed antibodies
occur in about 20% of patients with advanced head and neck squamous cell cancer …
occur in about 20% of patients with advanced head and neck squamous cell cancer …
Bitter Melon (Momordica Charantia), a Nutraceutical Approach for Cancer Prevention and Therapy
Cancer is the second leading cause of death worldwide. Many dietary plant products show
promising anticancer effects. Bitter melon or bitter gourd (Momordica charantia) is a nutrient …
promising anticancer effects. Bitter melon or bitter gourd (Momordica charantia) is a nutrient …
Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress
Developing strategies to activate tumor-cell-intrinsic immune response is critical for
improving tumor immunotherapy by exploiting tumor vulnerability. KDM4A, as a histone H3 …
improving tumor immunotherapy by exploiting tumor vulnerability. KDM4A, as a histone H3 …
[HTML][HTML] Oncogenic states dictate the prognostic and predictive connotations of intratumoral immune response
Background An immune active cancer phenotype typified by a T helper 1 (Th-1) immune
response has been associated with increased responsiveness to immunotherapy and …
response has been associated with increased responsiveness to immunotherapy and …
The current landscape of single-cell transcriptomics for cancer immunotherapy
Immunotherapies such as immune checkpoint blockade and adoptive cell transfer have
revolutionized cancer treatment, but further progress is hindered by our limited …
revolutionized cancer treatment, but further progress is hindered by our limited …