Biochemical analysis of oral fluids for disease detection

Z Khurshid, I Warsi, SF Moin, PD Slowey, M Latif… - Advances in clinical …, 2021 - Elsevier
The field of diagnostics using invasive blood testing represents the majority of diagnostic
tests used as part of routine health monitoring. The relatively recent introduction of salivary …

Saliva as biomarker for oral and chronic degenerative non-communicable diseases

M Basilicata, M Pieri, G Marrone, E Nicolai, M Di Lauro… - Metabolites, 2023 - mdpi.com
Saliva is a very complex fluid and it is essential to maintain several physiological processes
and functions, including oral health, taste, digestion and immunological defenses. Saliva …

Pepsin and oropharyngeal pH monitoring to diagnose patients with laryngopharyngeal reflux

M Weitzendorfer, SA Antoniou, P Schredl… - The …, 2020 - Wiley Online Library
Objectives The aim of this study was to compare the diagnostic accuracy of salivary pepsin
with oropharyngeal pH monitoring using the Restech measurement system (Dx‐pH) for the …

Portable and Rapid Fluorescence Turn-On Detection of Total Pepsin in Saliva Based on Strong Electrostatic Interactions

J Zhou, X Chen, Y Wei, R Lu, Z Wei, K Huang… - Analytical …, 2023 - ACS Publications
Salivary pepsin has been proposed as a promising diagnostic marker for gastroesophageal
reflux disease (GERD). However, the activity of human pepsin is strongly influenced by pH …

Saliva as an alternative to blood in the determination of uremic state in adult patients with chronic kidney disease: a systematic review and meta-analysis

RPCB Rodrigues, W de Andrade Vieira… - Clinical Oral …, 2020 - Springer
Objectives To assess whether salivary urea and creatinine levels accurately reflect their
serum levels in blood samples of adults to detect chronic kidney disease. Materials and …

Applying Lyon consensus criteria in the work‐up of patients with extra‐oesophageal symptoms–A multicentre retrospective study

F Calabrese, A Pasta, G Bodini… - Alimentary …, 2024 - Wiley Online Library
Background The diagnosis of gastro‐oesophageal reflux disease (GERD) based on
otolaryngologist's assessment of laryngoscopic findings remains contentious in terms of …

[HTML][HTML] Pepsin in saliva as a diagnostic marker for gastroesophageal reflux disease: a meta-analysis

Z Guo, H Wu, J Jiang, C Zhang - Medical science monitor …, 2018 - ncbi.nlm.nih.gov
Background Gastroesophageal reflux disease (GERD) is very common. Salivary pepsin
detection has previously been considered as a method for GERD diagnosis. We performed …

Diagnosis and management of laryngopharyngeal reflux

AJ Krause, R Yadlapati - Alimentary Pharmacology & …, 2024 - Wiley Online Library
Background Laryngopharyngeal reflux has classically referred to gastroesophageal reflux
leading to chronic laryngeal symptoms such as throat clearing, dysphonia, cough, globus …

Latin American consensus on diagnosis of gastroesophageal reflux disease

JA Olmos, JE Pandolfino, MM Piskorz… - …, 2024 - Wiley Online Library
Background Diagnosing gastroesophageal reflux disease (GERD) can be challenging given
varying symptom presentations, and complex multifactorial pathophysiology. The gold …

Salivary biomarkers and esophageal disorders

V Patel, S Ma, R Yadlapati - Diseases of the Esophagus, 2022 - academic.oup.com
Saliva is a complex physiologic fluid that contains an abundance of biological analytes, or
biomarkers. Recent research has shown that these biomarkers may be able to convey the …