The contribution of silk fibroin in biomedical engineering

C Lujerdean, GM Baci, AA Cucu, DS Dezmirean - Insects, 2022 - mdpi.com
Simple Summary In the medical area and beyond one of the most important biomaterials is
the silk fibroin (SF) produced by the Bombyx mori L. silkworm. This outstanding biopolymer …

Chemotherapy in patients with early breast cancer: clinical overview and management of long-term side effects

P Di Nardo, C Lisanti, M Garutti, S Buriolla… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Neo/adjuvant therapy for early-stage breast cancer has become increasingly
common in the last few decades; as a consequence, the number of breast cancer survivors …

[HTML][HTML] Single-cell analysis of dorsal root ganglia reveals metalloproteinase signaling in satellite glial cells and pain

R Tonello, AS Prudente, SH Lee, CF Cohen… - Brain, Behavior, and …, 2023 - Elsevier
Satellite glial cells (SGCs) are among the most abundant non-neuronal cells in dorsal root
ganglia (DRGs) and closely envelop sensory neurons that detect painful stimuli. However …

Efficacy of metformin in prevention of paclitaxel-induced peripheral neuropathy in breast cancer patients: A randomized controlled trial

HM Bakry, NO Mansour, TR ElKhodary… - Frontiers in …, 2023 - frontiersin.org
Background: Paclitaxel-induced peripheral neuropathy (PN) is a serious clinical problem
with no approved drug for prevention. This study aimed to examine the neuroprotective …

Effect of exercise before and/or during taxane-containing chemotherapy treatment on chemotherapy-induced peripheral neuropathy symptoms in women with breast …

R Brownson-Smith, ST Orange, N Cresti, K Hunt… - Journal of Cancer …, 2023 - Springer
Purpose To systematically review and meta-analyse the efficacy of exercise interventions
delivered before and/or during taxane-containing chemotherapy regimens on chemotherapy …

Neuroprotective mechanism of Ajugarin-I against Vincristine-Induced neuropathic pain via regulation of Nrf2/NF-κB and Bcl2 signalling

A Khan, B Shal, AU Khan, KU Shah, SS Zahra… - International …, 2023 - Elsevier
Vincristine (VCR) is a well-known chemotherapeutic agent that frequently triggers
neuropathic pain. Ajugarin-I (Aju-I) isolated from Ajuga bracteosa exerts antioxidant, anti …

Mitochondrial trafficking as a protective mechanism against chemotherapy drug-induced peripheral neuropathy: Identifying the key site of action

B Albin, K Qubbaj, AP Tiwari, P Adhikari, IH Yang - Life Sciences, 2023 - Elsevier
Aims Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect seen in
patients who have undergone most chemotherapy treatments to which there are currently no …

Mechanism-based pharmacological management of chemotherapy-induced neuropathic pain from preclinical studies to clinical prospective: platinum-based drugs …

N Zafari, M Velayati, M Maftooh… - Current …, 2023 - ingentaconnect.com
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a painful condition,
experienced by patients undergoing chemotherapy with some specific drugs, such as …

Duloxetine for prevention and treatment of chemotherapy-induced peripheral neuropathy (CIPN): systematic review and meta-analysis

R Chow, M Novosel, OW So, S Bellampalli… - BMJ Supportive & …, 2023 - spcare.bmj.com
Introduction Duloxetine has previously been reported to be promising in the setting of
chemotherapy-induced peripheral neuropathy (CIPN). The aim of this study was to conduct …

Peripheral neuropathy associated with monomethyl auristatin E-based antibody-drug conjugates

Z Fu, C Gao, T Wu, L Wang, S Li, Y Zhang, C Shi - Iscience, 2023 - cell.com
Since the successful approval of gemtuzumab ozogamicin, antibody-drug conjugates
(ADCs) have emerged as a pivotal category of targeted therapies for cancer. Among these …