echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …

Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization
approach that is particularly well-suited for unbiased (untargeted) metabolomics. In their …

Mass spectrometry–based quantitative proteomics has become an important component of
biological and clinical research. Although such analyses typically assume that a protein's …

Purpose To develop an absolute quantification method for membrane proteins, and to
construct a quantitative atlas of membrane transporter proteins in the blood–brain barrier …

Mass spectrometric based methods for absolute quantification of proteins, such as
QconCAT, rely on internal standards of stable-isotope labeled reference peptides, or" Q …

A decade after its inception, MALDI imaging mass spectrometry has become a unique
technique in the proteomics arsenal for biomarker hunting in a variety of diseases. At this …

The biomarkers are important in the Inflammatory Bowel Disease (IBD) to gain an objective
measurement of disease activity and severity, as well as prognostic indicator and outcome of …

Nanostructure initiator mass spectrometry (NIMS) is a recently introduced matrix-free
desorption/ionization platform that requires minimal sample preparation. Its application to …

Preterm birth (PTB; birth before 37 completed weeks of gestation) remains the major cause
of neonatal morbidity and mortality. The current generation of biomarkers predictive of PTB …

The proteomic approach is complementary to genomics and enables protein composition to
be investigated under various clinical conditions. Its application to the study of …