Taurine deficiency as a driver of aging
Aging is associated with changes in circulating levels of various molecules, some of which
remain undefined. We find that concentrations of circulating taurine decline with aging in …
remain undefined. We find that concentrations of circulating taurine decline with aging in …
Transcriptome-wide profiling and quantification of N6-methyladenosine by enzyme-assisted adenosine deamination
Abstract N 6-methyladenosine (m6A), the most abundant internal messenger RNA
modification in higher eukaryotes, serves myriad roles in regulating cellular processes …
modification in higher eukaryotes, serves myriad roles in regulating cellular processes …
Revisiting hematopoiesis: applications of the bulk and single-cell transcriptomics dissecting transcriptional heterogeneity in hematopoietic stem cells
Hematopoietic system (HS) is one of the most unique, adaptive and comprehensive
developmental systems on which various other body systems relies on. It consists of a …
developmental systems on which various other body systems relies on. It consists of a …
InsectBase 2.0: a comprehensive gene resource for insects
Y Mei, D Jing, S Tang, X Chen, H Chen… - Nucleic acids …, 2022 - academic.oup.com
Insects are the largest group of animals on the planet and have a huge impact on human life
by providing resources, transmitting diseases, and damaging agricultural crop production …
by providing resources, transmitting diseases, and damaging agricultural crop production …
[HTML][HTML] Revealing the history and mystery of RNA-Seq
A Gondane, HM Itkonen - Current Issues in Molecular Biology, 2023 - mdpi.com
Advances in RNA-sequencing technologies have led to the development of intriguing
experimental setups, a massive accumulation of data, and high demand for tools to analyze …
experimental setups, a massive accumulation of data, and high demand for tools to analyze …
Arbuscular mycorrhizal fungi heterokaryons have two nuclear populations with distinct roles in host–plant interactions
Arbuscular mycorrhizal fungi (AMF) are prominent root symbionts that can carry thousands
of nuclei deriving from two parental strains in a large syncytium. These co-existing genomes …
of nuclei deriving from two parental strains in a large syncytium. These co-existing genomes …
[HTML][HTML] Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA
Bisulfite sequencing (BS-seq) to detect 5-methylcytosine (5mC) is limited by lengthy reaction
times, severe DNA damage, overestimation of 5mC level and incomplete C-to-U conversion …
times, severe DNA damage, overestimation of 5mC level and incomplete C-to-U conversion …
Single-Nucleotide Resolution Mapping of N6-Methyladenine in Genomic DNA
CJ Ma, G Li, WX Shao, YH Min, P Wang… - ACS Central …, 2023 - ACS Publications
N 6-Methyladenine (6mA) is a naturally occurring DNA modification in both prokaryotes and
eukaryotes. Herein, we developed a deaminase-mediated sequencing (DM-seq) method for …
eukaryotes. Herein, we developed a deaminase-mediated sequencing (DM-seq) method for …
N6-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation
Summary N 6-methyladenosine (m 6 A) modifications play crucial roles in RNA metabolism.
How m 6 A regulates RNA polymerase II (RNA Pol II) transcription remains unclear. We find …
How m 6 A regulates RNA polymerase II (RNA Pol II) transcription remains unclear. We find …
[HTML][HTML] N6-methyladenosine in 5′ UTR does not promote translation initiation
E Guca, R Alarcon, MZ Palo, L Santos, S Alonso-Gil… - Molecular Cell, 2024 - cell.com
The most abundant N 6-methyladenosine (m 6 A) modification on mRNAs is installed non-
stoichiometrically across transcripts, with 5′ untranslated regions (5′ UTRs) being the …
stoichiometrically across transcripts, with 5′ untranslated regions (5′ UTRs) being the …