DNA damage detected with γH2AX in endometrioid adenocarcinoma cell lines

M Ikeda, A Kurose, E Takatori… - International …, 2010 - spandidos-publications.com
Phosphorylation of histone H2AX (γH2AX) is a sensitive marker of DNA damage, particularly
induction of DNA double-strand breaks. Using multiparameter cytometry we explored the …

Anti-tumor activity of heptaplatin in combination with 5-fluorouracil or paclitaxel against human head and neck cancer cells in vitro

JW Lee, JK Park, SH Lee, SY Kim, YB Cho… - Anti-Cancer …, 2006 - journals.lww.com
Heptaplatin (HTP), a newly developed platinum analog, has been approved for the
treatment of gastric cancers in South Korea. In this study we explored the potential of HTP for …

Apoptosis induced by 5-fluorouracil, cisplatin and paclitaxel are associated with p53 gene status in gastric cancer cell lines

N Matsuhashi, M Saio, A Matsuo… - International …, 2005 - spandidos-publications.com
In a recent study, we evaluated the efficacy and toxicity of 5-fluorouracil (5-FU), cisplatin
(CDDP), and 5-FU plus CDDP (FP treatment) in gastric cancer cell lines and examined the …

p53 dependence and apoptosis in response to FP treatment with p53-transfected colon cancer cell lines by use of thin layer collagen gel

N Matsuhashi, M Saio, A Matsuo… - Oncology …, 2004 - spandidos-publications.com
Abstract The combination of 5-fluorouracil (5-FU) plus Cisplatin (CDDP)(FP treatment)
possesses synergistic cytotoxicity against colon cancer. The molecular mechanisms by …

The antitumor activity of a novel fluorobenzamidine against dimethylhydrazine-induced colorectal cancer in rats

M Abdel-Rasol, NM El-Beih, SMM Yahya… - Anti-Cancer Agents …, 2020 - ingentaconnect.com
Background: Colorectal cancer is among the leading causes of death worldwide. The
incidence of deaths is expected to be 11.4 million in 2030. Objective: We aimed to evaluate …

[PDF][PDF] 抗肿瘤药阿霉素诱导Wnt 通路抑制因子的表达

腊蕾, 饶进军, 白福友, 吴曙光 - 生命科学研究, 2006 - smkx.hunnu.edu.cn
研究抗肿瘤药阿霉素对Wnt 通路抑制因子FrpHE (frizzled, related protein) 和DKK, 1 (Dickkopf,
1) 表达的作用. 将抗肿瘤药阿霉素加入到人肝癌HepG2 (HepG2, 含野生型p53; Hep3B, p53 …