Composition and functions of bacterial membrane vesicles

M Toyofuku, S Schild, M Kaparakis-Liaskos… - Nature Reviews …, 2023 - nature.com
Extracellular vesicles are produced by species across all domains of life, suggesting that
vesiculation represents a fundamental principle of living matter. In Gram-negative bacteria …

Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

[HTML][HTML] Bacterial extracellular vesicles as bioactive nanocarriers for drug delivery: Advances and perspectives

H Liu, Q Zhang, S Wang, W Weng, Y Jing, J Su - Bioactive Materials, 2022 - Elsevier
Nanosized extracellular vesicles derived from bacteria contain diverse cargo and transfer
intercellular bioactive molecules to cells. Due to their favorable intercellular interactions, cell …

Clostridium butyricum and its derived extracellular vesicles modulate gut homeostasis and ameliorate acute experimental colitis

L Ma, Q Shen, W Lyu, L Lv, W Wang, M Yu… - Microbiology …, 2022 - Am Soc Microbiol
Microbiological treatments are expected to have a role in the future management of
inflammatory bowel disease (IBD). Clostridium butyricum (C. butyricum) is a probiotic …

[HTML][HTML] Bacterial extracellular vesicles-based therapeutic strategies for bone and soft tissue tumors therapy

H Liu, H Zhang, Y Han, Y Hu, Z Geng, J Su - Theranostics, 2022 - ncbi.nlm.nih.gov
Bone and soft tissue tumors are complex mesenchymal neoplasms that seriously endanger
human health. Over the past decade, the relationship between microorganisms and human …

Fish disease and intestinal microbiota: A close and indivisible relationship

D Medina‐Félix, E Garibay‐Valdez… - Reviews in …, 2023 - Wiley Online Library
The gut microbiota is currently one of the most studied 'organs' in animals, and fish are no
exception. A complex diversity of microbes, including bacteria, archaea, yeast and fungus …

Fusobacterium nucleatum aggravates rheumatoid arthritis through FadA-containing outer membrane vesicles

M Hong, Z Li, H Liu, S Zheng, F Zhang, J Zhu, H Shi… - Cell Host & Microbe, 2023 - cell.com
Rheumatoid arthritis (RA) is an autoimmune disorder that has been associated with the gut
microbiota. However, whether and how the gut microbiota plays a pathogenic role in RA …

[HTML][HTML] Engineered bacterial extracellular vesicles for osteoporosis therapy

H Liu, M Li, T Zhang, X Liu, H Zhang, Z Geng… - Chemical Engineering …, 2022 - Elsevier
Osteoporosis (OP) is a systemic bone disease characterized by reduction of bone mass and
destruction of structure, which can easily lead to fragility fractures. Over the past decade, an …

Gut bacterial extracellular vesicles: important players in regulating intestinal microenvironment

X Liang, N Dai, K Sheng, H Lu, J Wang, L Chen… - Gut …, 2022 - Taylor & Francis
Intestinal microenvironment dysbiosis is one of the major causes of diseases, such as
obesity, diabetes, inflammatory bowel disease, and colon cancer. Microbiota-based …

Bacterial extracellular vesicles: an emerging avenue to tackle diseases

J Xie, F Haesebrouck, L Van Hoecke… - Trends in …, 2023 - cell.com
A growing body of research, especially in recent years, has shown that bacterial
extracellular vesicles (bEVs) are one of the key underlying mechanisms behind the …