[HTML][HTML] Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway
H Sun, C Tang, SH Chung, XQ Ye, Y Makusheva… - Cell reports, 2022 - cell.com
Dendritic cell immunoreceptor (DCIR; Clec4a2), a member of the C-type lectin receptor
family, plays important roles in homeostasis of the immune and bone systems. However, the …
family, plays important roles in homeostasis of the immune and bone systems. However, the …
Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway
Y Wang, Z Shou, H Fan, M Xu, Q Chen… - Bioscience …, 2019 - portlandpress.com
Oxymatrine (OMT) is an important quinoxaline alkaloid that has a wide range of
pharmacological effects and has been shown to alleviate ulcerative colitis due to its …
pharmacological effects and has been shown to alleviate ulcerative colitis due to its …
GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine intoxicated mice
LM Kosloski, EA Kosmacek, KE Olson… - Journal of …, 2013 - Elsevier
Innate and adaptive immune responses can speed nigrostriatal neurodegeneration in
Parkinson's disease (PD). We posit that GM-CSF can attenuate such responses. In 1-methyl …
Parkinson's disease (PD). We posit that GM-CSF can attenuate such responses. In 1-methyl …
Dietary Chito-oligosaccharides Improve Intestinal Immunity via Regulating Microbiota and Th17/Treg Balance-Related Immune Signaling in Piglets Challenged by …
M Yu, T Meng, W He, H Huang, C Liu… - Journal of Agricultural …, 2021 - ACS Publications
This study was conducted to investigate how chito-oligosaccharides (COSs) affect the
growth performance and immune stress response and to further explain their mechanisms. A …
growth performance and immune stress response and to further explain their mechanisms. A …
[HTML][HTML] Circular RNAs in inflammatory bowel disease
J Lun, J Guo, M Yu, H Zhang, J Fang - Frontiers in Immunology, 2023 - frontiersin.org
Inflammatory bowel disease (IBD) is a term encompassing a few chronic inflammatory
disorders that leads to damage of the intestinal tract. Although much progress has been …
disorders that leads to damage of the intestinal tract. Although much progress has been …
Novel perspectives on therapeutic modulation of the gut microbiota
JL McCarville, A Caminero… - Therapeutic advances in …, 2016 - journals.sagepub.com
The gut microbiota contributes to the maintenance of health and, when disrupted, may drive
gastrointestinal and extragastrointestinal disease. This can occur through direct pathways …
gastrointestinal and extragastrointestinal disease. This can occur through direct pathways …
[HTML][HTML] Gastrointestinal dopamine in inflammatory bowel diseases: a systematic review
M Kurnik-Łucka, P Pasieka, P Łączak… - International Journal of …, 2021 - mdpi.com
Background: an increased prevalence of gastro-duodenal ulceration was described almost
sixty years ago as prodromal to idiopathic Parkinson's disease, while duodenal ulcers have …
sixty years ago as prodromal to idiopathic Parkinson's disease, while duodenal ulcers have …
[HTML][HTML] Microbiota as key factors in inflammatory bowel disease
Z White, I Cabrera, I Kapustka, T Sano - Frontiers in Microbiology, 2023 - frontiersin.org
Inflammatory Bowel Disease (IBD) is characterized by prolonged inflammation of the
gastrointestinal tract, which is thought to occur due to dysregulation of the immune system …
gastrointestinal tract, which is thought to occur due to dysregulation of the immune system …
[HTML][HTML] rSj16 protects against DSS-induced colitis by inhibiting the PPAR-α signaling pathway
L Wang, H Xie, L Xu, Q Liao, S Wan, Z Yu, D Lin… - Theranostics, 2017 - ncbi.nlm.nih.gov
Background: Epidemiologic studies and animal model experiments have shown that
parasites have significant modulatory effects on autoimmune disorders, including …
parasites have significant modulatory effects on autoimmune disorders, including …
[HTML][HTML] Inflammatory bowel disease: therapeutic limitations and prospective of the stem cell therapy
R Mishra, P Dhawan, AS Srivastava… - World journal of stem …, 2020 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), consisting primarily of ulcerative colitis and Crohn's
disease, is a group of debilitating auto-immune disorders, which also increases the risk of …
disease, is a group of debilitating auto-immune disorders, which also increases the risk of …