[HTML][HTML] Antigen-specific Treg cells in immunological tolerance: implications for allergic diseases

A Abdel-Gadir, AH Massoud, TA Chatila - F1000Research, 2018 - ncbi.nlm.nih.gov
Allergic diseases are chronic inflammatory disorders in which there is failure to mount
effective tolerogenic immune responses to inciting allergens. The alarming rise in the …

Predicting diagnostic biomarkers associated with immune infiltration in Crohn's disease based on machine learning and bioinformatics

W Bao, L Wang, X Liu, M Li - European Journal of Medical Research, 2023 - Springer
Objective The objective of this study is to investigate potential biomarkers of Crohn's disease
(CD) and the pathological importance of infiltration of associated immune cells in disease …

Polydatin alleviates DSS‐and TNBS‐induced colitis by suppressing Th17 cell differentiation via directly inhibiting STAT3

YJ Liu, WH Xu, LM Fan, YQ Zhang, W Xu… - Phytotherapy …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a non‐specific chronic intestinal inflammatory disease,
often presenting with abdominal pain, diarrhea, bloody stool, anorexia, and body loss. It is …

Correction of defective T-regulatory cells from patients with Crohn's disease by ex vivo ligation of retinoic acid receptor-α

R Goldberg, C Scotta, D Cooper, E Nissim-Eliraz, E Nir… - Gastroenterology, 2019 - Elsevier
Background & Aims Crohn's disease (CD) is characterized by an imbalance of effector and
regulatory T cells in the intestinal mucosa. The efficacy of anti-adhesion therapies led us to …

Tryptophan metabolism, regulatory T cells, and inflammatory bowel disease: a mini review

X Ding, P Bin, W Wu, Y Chang… - Mediators of inflammation, 2020 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract resulting from the homeostasis imbalance of intestinal microenvironment, immune …

[HTML][HTML] Lactobacillus plantarum CBT LP3 ameliorates colitis via modulating T cells in mice

DH Kim, S Kim, JB Ahn, JH Kim, HW Ma… - International Journal of …, 2020 - Elsevier
Lactobacillus plantarum has been identified as a probiotic bacterium owing to its role in
immune regulation and maintenance of intestinal permeability. Here, we investigated the …

T lymphocyte dynamics in inflammatory bowel diseases: role of the microbiome

CB Larmonier, KW Shehab… - BioMed research …, 2015 - Wiley Online Library
Humans have coevolved with a complex community of bacterial species also referred to as
the microbiome, which reciprocally provides critical contributions to human metabolism and …

The role of salt for immune cell function and disease

R Willebrand, M Kleinewietfeld - Immunology, 2018 - Wiley Online Library
The immune system evolved to protect organisms from invading pathogens. A network of pro‐
and anti‐inflammatory cell types equipped with special effector molecules guarantees …

Tregs in autoimmunity: insights into intrinsic brake mechanism driving pathogenesis and immune homeostasis

KJ Bednar, JH Lee, T Ort - Frontiers in Immunology, 2022 - frontiersin.org
CD4+ CD25highFoxp3+ regulatory T-cells (Tregs) are functionally characterized for their
ability to suppress the activation of multiple immune cell types and are indispensable for …

Chimonanthus nitens Oliv. Leaf Granule Ameliorates DSS-Induced Acute Colitis Through Treg Cell Improvement, Oxidative Stress Reduction, and Gut Microflora …

JQ Huang, SY Wei, N Cheng, YB Zhong… - Frontiers in Cellular …, 2022 - frontiersin.org
The rising incidence of ulcerative colitis has become a new challenge for public health.
Chimonanthus nitens Oliv. leaf granule (COG) is a natural medicine used for the treatment of …