Efficacy of pentavalent antimoniate intralesional infiltration therapy for cutaneous leishmaniasis: A systematic review

NC Brito, A Rabello, GF Cota - PloS one, 2017 - journals.plos.org
Background The mainstays of cutaneous leishmaniasis (CL) treatment, in several world
regions, are pentavalent antimony (Sbv) compounds administered parenterally, despite their …

Diagnosis and treatment of leishmaniasis: clinical practice guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical …

N Aronson, BL Herwaldt, M Libman… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that leishmaniasis guidelines cannot always account for individual
variation among patients. They are not intended to supplant physician judgment with respect …

Pentavalent antimonials combined with other therapeutic alternatives for the treatment of cutaneous and mucocutaneous leishmaniasis: A systematic review

TRN Berbert, TFP Mello, P Wolf Nassif… - Dermatology …, 2018 - Wiley Online Library
The first choice drugs for the treatment of cutaneous and mucocutaneous leishmaniasis are
pentavalent antimonials, sodium stibogluconate, or meglumine antimoniate. However, the …

Computer-aided drug design using sesquiterpene lactones as sources of new structures with potential activity against infectious neglected diseases

C Herrera Acevedo, L Scotti, M Feitosa Alves… - Molecules, 2017 - mdpi.com
This review presents an survey to the biological importance of sesquiterpene lactones (SLs)
in the fight against four infectious neglected tropical diseases (NTDs)—leishmaniasis …

[HTML][HTML] Intralesional pentamidine: a novel therapy for single lesions of Bolivian cutaneous leishmaniasis

J Soto, D Paz, D Rivero, P Soto, J Quispe… - The American journal …, 2016 - ncbi.nlm.nih.gov
A novel therapy, intralesional (IL) pentamidine, was compared to intralesional therapy with
antimony (ILSb), a World Health Organization–recommended therapy, for single Bolivian …

An old drug and different ways to treat cutaneous leishmaniasis: intralesional and intramuscular meglumine antimoniate in a reference center, Rio de Janeiro, Brazil

C Oliveira-Ribeiro, MIF Pimentel… - PLoS Neglected …, 2021 - journals.plos.org
Background Treatment of cutaneous leishmaniasis (CL) remains challenging since the
drugs currently used are quite toxic, thus contributing to lethality unrelated to the disease …

[HTML][HTML] Intralesional meglumine antimoniate for the treatment of localised cutaneous leishmaniasis: a retrospective review of a Brazilian referral centre

RE Silva, A Toledo Júnior, MC Senna… - Memórias do Instituto …, 2016 - SciELO Brasil
Although intralesional meglumine antimoniate (MA) infiltration is considered an option for
cutaneous leishmaniasis (CL) therapy and is widely used in the Old World, there have been …

Meglumine antimoniate is more effective than sodium stibogluconate in the treatment of cutaneous leishmaniasis

Y Yesilova, HA Surucu, N Ardic, M Aksoy… - Journal of …, 2016 - Taylor & Francis
Sodium stibogluconate (SSG, Pentostam) and meglumine antimoniate (MA, Glucantime) are
two antimonials that are widely used to treat cutaneous leishmaniasis (CL), but the relative …

Comparison between systemic and intralesional meglumine antimoniate therapy in a primary health care unit

MC de Oliveira Duque, JJQ Silva, PAO Soares… - Acta tropica, 2019 - Elsevier
Cutaneous leishmaniasis (CL) is not a life-threatening condition. However, its treatment can
cause serious adverse effects and may sometimes lead to death. Recently, safer local …

Meglumine antimoniate intralesional infiltration for localised cutaneous leishmaniasis: a single arm, open label, phase II clinical trial

DB Ramalho, RE Silva, MCR Senna… - Memórias do Instituto …, 2018 - SciELO Brasil
BACKGROUND Cutaneous leishmaniasis (CL) is a world-wide health problem which
currently lacks effective, affordable and easy to use therapy. Recently, the meglumine …