Acute myocardial infarction (AMI) is a threat to human life and physical health worldwide.
Timely reperfusion is very important to limit infarct size and protect ischemic myocardium …

Ischemic heart failure (IHF) is a leading cause of morbidity and mortality worldwide, for
which heart transplantation remains the only definitive treatment. IHF manifests from …

Context Shenlian extract (SL) is a combination of Salvia miltiorrhiza Bge.(Labiatae) and
Andrographis paniculata (Burm. F.) Wall. Ex Nees (Acanthaceae) extracts, which promote …

The present study hypothesizes that the ischemic insults activate epicardial adipose tissue-
derived stem cells (EATDS) to secrete extracellular vesicles (EVs) packed with regenerative …

New blood vessel formation is a key component of the cardiac repair process after
myocardial infarction (MI). Hypoxia following MI is a major driver of angiogenesis in the …

Background Despite promising results in clinical studies, the mechanism for the beneficial
effects of allogenic cell-based therapies remains unclear. Macrophages are not only critical …

Cardiovascular diseases (CVDs), which encompass a myriad of pathological conditions that
affect the heart and/or the blood vessels, remain the major cause of morbidity and mortality …

Small extracellular vesicles (sEV) derived from various cell sources have been
demonstrated to enhance cardiac function in preclinical models of myocardial infarction (MI) …

Acute myocardial infarction (AMI) reperfusion is associated with ischemia/reperfusion (I/R)
injury, which leads to enlarged myocardial infarction size, poor healing of the infarcted …

Heart failure remains a leading cause of mortality. Therapeutic intervention for heart failure
would benefit from targeted delivery to the damaged heart tissue. Here, we applied in vivo …