A timeline of tumour-associated macrophage biology
L Cassetta, JW Pollard - Nature Reviews Cancer, 2023 - nature.com
Tumour progression is modulated by the local microenvironment. This environment is
populated by many immune cells, of which macrophages are among the most abundant …
populated by many immune cells, of which macrophages are among the most abundant …
Toll-like receptor signaling and its role in cell-mediated immunity
Innate immunity is the first defense system against invading pathogens. Toll-like receptors
(TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition …
(TLRs) are well-defined pattern recognition receptors responsible for pathogen recognition …
Targeting macrophages in cancer immunotherapy
Z Duan, Y Luo - Signal transduction and targeted therapy, 2021 - nature.com
Immunotherapy is regarded as the most promising treatment for cancers. Various cancer
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
immunotherapies, including adoptive cellular immunotherapy, tumor vaccines, antibodies …
Pattern recognition receptors in health and diseases
D Li, M Wu - Signal transduction and targeted therapy, 2021 - nature.com
Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged …
Activation and evasion of type I interferon responses by SARS-CoV-2
X Lei, X Dong, R Ma, W Wang, X Xiao, Z Tian… - Nature …, 2020 - nature.com
The pandemic of COVID-19 has posed an unprecedented threat to global public health.
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …
However, the interplay between the viral pathogen of COVID-19, SARS-CoV-2, and host …
Toll‐like receptors (TLRs): structure, functions, signaling, and role of their polymorphisms in colorectal cancer susceptibility
AS Sameer, S Nissar - BioMed Research International, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are the important mediators of inflammatory pathways in the gut
which play a major role in mediating the immune responses towards a wide variety of …
which play a major role in mediating the immune responses towards a wide variety of …
Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
[HTML][HTML] The many faces of the anti-COVID immune response
SA Vardhana, JD Wolchok - Journal of Experimental Medicine, 2020 - rupress.org
Disclosures: SA Vardhana reported personal fees from Immunai and personal fees from
ADC Therapeutics outside the submitted work; in addition, SA Vardhana had a patent to …
ADC Therapeutics outside the submitted work; in addition, SA Vardhana had a patent to …
Toll-like receptors and the control of immunity
KA Fitzgerald, JC Kagan - Cell, 2020 - cell.com
The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …
Toll-like receptors activation, signaling, and targeting: an overview
SR El-Zayat, H Sibaii, FA Mannaa - Bulletin of the National Research …, 2019 - Springer
Abstract Background Toll-like receptors (TLRs) are an important family of receptors that
constitute the first line of defense system against microbes. They can recognize both …
constitute the first line of defense system against microbes. They can recognize both …