Phenolic compounds are natural phytochemicals that have recently reported numerous
health benefits. Resveratrol, curcumin, and quercetin have recently received the most …

Pharmacoresistance of cancer cells to many drugs used in chemotherapy remains a major
challenge for the treatment of cancer. Multidrug resistance transporters, especially ATP …

Bioactive natural products (BNPs) are the marrow of medicinal plants, which are the
secondary metabolites of organisms and have been the most famous drug discovery …

Various literature data show how a diet rich in vegetables could reduce the incidence of
several cancers due to the contribution of the natural polyphenols contained in them …

Bone reconstruction includes a steady state system of bone formation and bone absorption.
This tight coupling requires subtle coordination between osteoblasts and osteoclasts. If this …

The existence of a tight relationship between inflammation and epigenetics that in primary
breast tumor cells can lead to tumor progression and the formation of bone metastases was …

Background Osteosarcoma is a malignant bone tumor with a high rate of lung metastasis
and mortality. It has been demonstrated that resveratrol can inhibit tumor proliferation and …

This study explored the co-delivery of curcumin (CUR) and resveratrol (RV) using folic acid-
conjugated poly (glycerol adipate)-based nanoparticles (FPPC NPs) to enhance their …

Osteosarcoma (OSA) is the most common pediatric malignant bone tumor. Although surgery
together with neoadjuvant/adjuvant chemotherapy has improved survival for localized OSA …

This study adopts an in vitro method to recapitulate the behavior of Saos‐2 cells, using a
system composed of a perfusion bioreactor and poly‐L‐lactic acid (PLLA) scaffold fabricated …