Ferroptosis inhibitors: past, present and future

L Zhang, YL Luo, Y Xiang, XY Bai, RR Qiang… - Frontiers in …, 2024 - frontiersin.org
Ferroptosis is a non-apoptotic mode of programmed cell death characterized by iron
dependence and lipid peroxidation. Since the ferroptosis was proposed, researchers have …

Impact of inorganic/organic nanomaterials on the immune system for disease treatment

J Han, K Mao, YG Yang, T Sun - Biomaterials Science, 2024 - pubs.rsc.org
The study of nanomaterials' nature, function, and biocompatibility highlights their potential in
drug delivery, imaging, diagnostics, and therapeutics. Advancements in nanotechnology …

[HTML][HTML] Use of Mn3O4 nanozyme to improve cotton salt tolerance

J Liu, J Gu, J Hu, H Ma, Y Tao, G Li, L Yue… - Plant biotechnology …, 2023 - ncbi.nlm.nih.gov
Cotton is an important fibre and oil crop across the globe. Salinity is a global issue limiting
efficient crop production. Especially, salinity is a big threat for cotton production in China …

ZBP1-mediated apoptosis and inflammation exacerbate steatotic liver ischemia-reperfusion injury

R Liu, H Cao, S Zhang, M Cai, T Zou… - The Journal of …, 2024 - Am Soc Clin Investig
There is increasing need to expand availability of donor liver grafts, including steatotic livers.
However, the current use of steatotic grafts in liver transplantation is less acceptable due to …

Inhibition of lysosomal TRPML1 channel eliminates breast cancer stem cells by triggering ferroptosis

C Fan, H Wu, X Du, C Li, W Zeng, L Qu, C Cang - Cell Death Discovery, 2024 - nature.com
Cancer stem cells (CSCs) are a sub-population of cells possessing high tumorigenic
potential, which contribute to therapeutic resistance, metastasis and recurrence. Eradication …

Ultrasmall Nanodots with Dual Anti‐Ferropototic Effect for Acute Kidney Injury Therapy

F Zeng, Y Qin, S Nijiati, Y Liu, J Ye, H Shen… - Advanced …, 2024 - Wiley Online Library
Ferroptosis is known to mediate the pathogenesis of chemotherapeutic drug‐induced acute
kidney injury (AKI); however, leveraging the benefits of ferroptosis‐based treatments for …

Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition

J Ji, Y Jin, S Ma, Y Zhu, X Bi, Q You… - Journal of Medicinal …, 2024 - ACS Publications
Ferroptosis, a distinctive form of programmed cell death, has been implicated in numerous
pathological conditions, and its inhibition is considered a promising therapeutic strategy …

Polyacrylic Acid‐Coated Selenium‐Doped Carbon Dots Inhibit Ferroptosis to Alleviate Chemotherapy‐Associated Acute Kidney Injury

J Li, C Fu, B Feng, Q Liu, J Gu, MN Khan… - Advanced …, 2024 - Wiley Online Library
Cisplatin‐associated acute kidney injury (AKI) is a severe clinical syndrome that significantly
restricts the chemotherapeutic application of cisplatin in cancer patients. Ferroptosis, a …

Nanomedicines Targeting Ferroptosis to Treat Stress-Related Diseases

H Kang, F Meng, F Liu, M Xie, H Lai, P Li… - International Journal of …, 2024 - Taylor & Francis
Ferroptosis, a unique form of regulated cell death driven by iron-dependent lethal lipid
peroxidation, is implicated in various stress-related diseases like neurodegeneration …

Immuno‐Nanocomplexes Target Heterogenous Network of Inflammation and Immunity in Myocardial Infarction

F Su, W Ye, Y Shen, Y Xie, C Zhang, Q Zhang… - Advanced …, 2024 - Wiley Online Library
Despite the proceeds in the management of acute myocardial infarction (AMI), the current
therapeutic landscape still suffers from limited success in the clinic. Exaggerated …