As an essential component of our innate immune system, the complement system is
responsible for our defense against pathogens. The complement cascade has complex …

Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing
term that describes cognitive impairment due to cerebrovascular origins. With the …

Background Vascular dementia (VD) is the second most common type of dementia after
Alzheimer's disease. β-asarone, a major component of Acorus tatarinowii Schott, is …

Chemotherapeutic agents such as doxorubicin, cyclophosphamide, fluorouracil, and
cisplatin are commonly used to treat a variety of cancers and often result in chemobrain …

Background Alterations in nitric oxide (NO) synthesis have been reported in Alzheimer's
disease and vascular dementia. However, as the measurement of NO in biological samples …

Background Cerebral ischemia has the characteristics of high incidence, mortality, and
disability, which seriously damages people's health. Cerebral ischemia-reperfusion injury is …

Introduction Although the association between Alzheimer's disease (AD) and constipation is
controversial, its causality and underlying mechanisms remain unknown. Objectives To …

Microglia-mediated chronic neuroinflammation has been associated with cognitive decline
induced by rotenone, a well-known neurotoxic pesticide used in agriculture. However, the …

Introduction Women with hypertensive disorders of pregnancy (HDP) have an increased risk
of cardiovascular disease. Whether HDP is also associated with later‐life dementia has not …

Abstract Ethnopharmacological relevance Qinzhizhudan Formula (QZZD) is composed of
Scutellaria baicalensis Georgi (Huang Qin) extract, Gardenia jasminoides (Zhizi) extract and …