Thyroid cancer mortality and incidence: a global overview

C La Vecchia, M Malvezzi, C Bosetti… - … journal of cancer, 2015 - Wiley Online Library
In most areas of the world, thyroid cancer incidence has been appreciably increasing over
the last few decades, whereas mortality has steadily declined. We updated global trends in …

Molecular pathogenesis and mechanisms of thyroid cancer

M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

[HTML][HTML] Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

C Tomasetti, B Vogelstein - Science, 2015 - science.org
Some tissue types give rise to human cancers millions of times more often than other tissue
types. Although this has been recognized for more than a century, it has never been …

Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next‐generation …

YE Nikiforov, SE Carty, SI Chiosea, C Coyne… - Cancer, 2014 - Wiley Online Library
BACKGROUND Fine‐needle aspiration (FNA) cytology is a common approach to evaluating
thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers …

American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer

RC Smallridge, KB Ain, SL Asa, KC Bible, JD Brierley… - Thyroid, 2012 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum …

[HTML][HTML] Papillary thyroid cancer prognosis: An evolving field

S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …

Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer

MN Nikiforova, AI Wald, S Roy… - The Journal of …, 2013 - academic.oup.com
Objectives: Next-generation sequencing (NGS) allows for high-throughput sequencing
analysis of large regions of the human genome. We explored the use of targeted NGS for …

[HTML][HTML] Novel targeted therapies and immunotherapy for advanced thyroid cancers

GE Naoum, M Morkos, B Kim, W Arafat - Molecular cancer, 2018 - Springer
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …

Redifferentiation of Iodine-Refractory BRAF V600E-Mutant Metastatic Papillary Thyroid Cancer with Dabrafenib

SM Rothenberg, DG McFadden, EL Palmer… - Clinical Cancer …, 2015 - AACR
Purpose: To determine whether the selective BRAF inhibitor, dabrafenib, can stimulate
radioiodine uptake in BRAF V600E-mutated unresectable or metastatic iodine-refractory …