Thyroid cancer mortality and incidence: a global overview
In most areas of the world, thyroid cancer incidence has been appreciably increasing over
the last few decades, whereas mortality has steadily declined. We updated global trends in …
the last few decades, whereas mortality has steadily declined. We updated global trends in …
Molecular pathogenesis and mechanisms of thyroid cancer
M Xing - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …
understanding its molecular pathogenesis in recent years, as best exemplified by the …
[HTML][HTML] Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
I Landa, T Ibrahimpasic, L Boucai… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
(ATC) are rare and frequently lethal tumors that so far have not been subjected to …
Variation in cancer risk among tissues can be explained by the number of stem cell divisions
C Tomasetti, B Vogelstein - Science, 2015 - science.org
Some tissue types give rise to human cancers millions of times more often than other tissue
types. Although this has been recognized for more than a century, it has never been …
types. Although this has been recognized for more than a century, it has never been …
Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by ThyroSeq v2 next‐generation …
YE Nikiforov, SE Carty, SI Chiosea, C Coyne… - Cancer, 2014 - Wiley Online Library
BACKGROUND Fine‐needle aspiration (FNA) cytology is a common approach to evaluating
thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers …
thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology, which hampers …
American Thyroid Association guidelines for management of patients with anaplastic thyroid cancer
RC Smallridge, KB Ain, SL Asa, KC Bible, JD Brierley… - Thyroid, 2012 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum …
cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum …
[HTML][HTML] Papillary thyroid cancer prognosis: An evolving field
S Ulisse, E Baldini, A Lauro, D Pironi, D Tripodi, E Lori… - Cancers, 2021 - mdpi.com
Simple Summary Over the last couple of decades, the prognostic stratification systems of
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …
differentiated thyroid cancer (DTC) patients have been revised several times in an attempt to …
Targeted next-generation sequencing panel (ThyroSeq) for detection of mutations in thyroid cancer
MN Nikiforova, AI Wald, S Roy… - The Journal of …, 2013 - academic.oup.com
Objectives: Next-generation sequencing (NGS) allows for high-throughput sequencing
analysis of large regions of the human genome. We explored the use of targeted NGS for …
analysis of large regions of the human genome. We explored the use of targeted NGS for …
[HTML][HTML] Novel targeted therapies and immunotherapy for advanced thyroid cancers
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …
Redifferentiation of Iodine-Refractory BRAF V600E-Mutant Metastatic Papillary Thyroid Cancer with Dabrafenib
SM Rothenberg, DG McFadden, EL Palmer… - Clinical Cancer …, 2015 - AACR
Purpose: To determine whether the selective BRAF inhibitor, dabrafenib, can stimulate
radioiodine uptake in BRAF V600E-mutated unresectable or metastatic iodine-refractory …
radioiodine uptake in BRAF V600E-mutated unresectable or metastatic iodine-refractory …