[HTML][HTML] Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast …

HJ Burstein, G Curigliano, B Thürlimann, WP Weber… - Annals of oncology, 2021 - Elsevier
The 17th St Gallen International Breast Cancer Consensus Conference in 2021 was held
virtually, owing to the global COVID-19 pandemic. More than 3300 participants took part in …

Assessment of Ki67 in breast cancer: updated recommendations from the international Ki67 in breast cancer working group

TO Nielsen, SCY Leung, DL Rimm… - JNCI: Journal of the …, 2021 - academic.oup.com
Abstract Ki67 immunohistochemistry (IHC), commonly used as a proliferation marker in
breast cancer, has limited value for treatment decisions due to questionable analytical …

Biomarkers for adjuvant endocrine and chemotherapy in early-stage breast cancer: ASCO guideline update

F Andre, N Ismaila, KH Allison, WE Barlow… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To update recommendations on appropriate use of breast cancer biomarker
assay results to guide adjuvant endocrine and chemotherapy decisions in early-stage breast …

[HTML][HTML] Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study

N Harbeck, P Rastogi, M Martin, SM Tolaney… - Annals of …, 2021 - Elsevier
Background Adjuvant abemaciclib combined with endocrine therapy (ET) previously
demonstrated clinically meaningful improvement in invasive disease-free survival (IDFS) …

Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

S Loibl, F André, T Bachelot, CH Barrios… - Annals of …, 2024 - annalsofoncology.org
Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆
- Annals of Oncology Skip to Main Content Advertisement Annals of Oncology European …

[HTML][HTML] Systemic therapy for early-stage breast cancer: learning from the past to build the future

E Agostinetto, J Gligorov, M Piccart - Nature Reviews Clinical Oncology, 2022 - nature.com
The treatment of breast cancer has improved dramatically over the past century, from a
strictly surgical approach to a coordinated one, including local and systemic therapies …

Endocrine therapy response and 21-gene expression assay for therapy guidance in HR+/HER2–early breast cancer

UA Nitz, O Gluz, S Kümmel, M Christgen… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To our knowledge, WSG-ADAPT-HR+/HER2–(ClinicalTrials. gov identifier:
NCT01779206; n= 5,625 registered) is the first trial combining the 21-gene expression …

Understanding breast cancer complexity to improve patient outcomes: the St Gallen international consensus conference for the primary therapy of individuals with …

G Curigliano, HJ Burstein, M Gnant, S Loibl… - Annals of …, 2023 - Elsevier
The 18th St Gallen International Breast Cancer Conference held in March 2023, in Vienna,
Austria, assessed significant new findings for local and systemic therapies for early breast …

[HTML][HTML] Ki-67 as a prognostic biomarker in invasive breast cancer

MG Davey, SO Hynes, MJ Kerin, N Miller, AJ Lowery - Cancers, 2021 - mdpi.com
Simple Summary In breast cancer development, the expression of Ki-67 is strongly
associated with cancer proliferation and is a known indicator of prognosis and outcome. Ki …

[HTML][HTML] Molecular profiling of aromatase inhibitor sensitive and resistant ER+ HER2-postmenopausal breast cancers

EF Schuster, E Lopez-Knowles, A Alataki… - Nature …, 2023 - nature.com
Aromatase inhibitors (AIs) reduce recurrences and mortality in postmenopausal patients with
oestrogen receptor positive (ER+) breast cancer (BC), but> 20% of patients will eventually …