Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …

COVID-19 is a primary respiratory illness that is frequently complicated by systemic
involvement of the vasculature. Vascular involvement leads to an array of complications …

Background Long-COVID is characterized by prolonged, diffuse symptoms months after
acute COVID-19. Accurate diagnosis and targeted therapies for Long-COVID are lacking …

Background Severe COVID‐19 disease is associated with thrombotic complications and
extensive fibrin deposition. This study investigates whether the hemostatic complications in …

The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

Plasminogen activator inhibitor 1 (PAI-1), a SERPIN inhibitor, is primarily known for its
regulation of fibrinolysis. However, it is now known that this inhibitor functions and …

Abstract Coronavirus disease 2019 (COVID-19) is regarded as an endothelial disease
(endothelialitis) with its patho-mechanism being incompletely understood. Emerging …

December 2019 will never be forgotten in the history of medicine when an outbreak of
pneumonia of unknown etiology in Wuhan, China sooner or later prompted the World Health …

The coagulation, fibrinolytic, anticoagulation, and complement systems are in delicate
balance with the vessel wall endothelium ensuring appropriate hemostasis. Coagulopathy …

Introduction Coagulation parameters are important determinants for COVID-19 infection. We
conducted meta-analysis to assess the association between early hemostatic parameters …