The key differences between human papillomavirus-positive and-negative head and neck cancers: biological and clinical implications

SF Powell, L Vu, WC Spanos, D Pyeon - Cancers, 2021 - mdpi.com
Simple Summary Head and neck cancer (HNC) is the sixth most common cancer, causing
almost half a million deaths worldwide every year. The two subtypes of HNC are distinctly …

Biological prognostic value of miR-155 for survival outcome in head and neck squamous cell carcinomas: systematic review, meta-analysis and trial sequential …

M Dioguardi, F Spirito, D Sovereto, L La Femina… - Biology, 2022 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) is the neoplasm with
the highest incidence in the head and neck regions. More than 350,000 new cases of …

Current and future trends in molecular biomarkers for diagnostic, prognostic, and predictive purposes in non-melanoma skin cancer

TK Nikolouzakis, L Falzone, K Lasithiotakis… - Journal of Clinical …, 2020 - mdpi.com
Skin cancer represents the most common type of cancer among Caucasians and presents in
two main forms: melanoma and non-melanoma skin cancer (NMSC). NMSC is an umbrella …

Insights into the mechanisms of action of proanthocyanidins and anthocyanins in the treatment of nicotine-induced non-small cell lung cancer

NA Alsharairi - International journal of molecular sciences, 2022 - mdpi.com
In traditional medicine, different parts of plants, including fruits, have been used for their anti-
inflammatory and anti-oxidative properties. Plant-based foods, such as fruits, seeds and …

Exosomal MicroRNA-223, MicroRNA-146, and MicroRNA-21 profiles and biochemical changes in laryngeal cancer

S Genc, T Yagci, DP Vageli, R Dundar… - ACS Pharmacology & …, 2023 - ACS Publications
Laryngeal squamous cell carcinoma (LSCC) is one of the most aggressive cancers, and its
early diagnosis is urgent. Exosomes are believed to have diagnostic significance in cancer …

Patterns of carbon-bound exogenous compounds impact disease pathophysiology in lung cancer subtypes in different ways

J Shen, N Sun, J Wang, P Zens, T Kunzke, A Buck… - ACS …, 2023 - ACS Publications
Carbon-bound exogenous compounds, such as polycyclic aromatic hydrocarbons (PAHs),
tobacco-specific nitrosamines, aromatic amines, and organohalogens, are known to affect …

Fusobacterium nucleatum impairs DNA mismatch repair and stability in patients with squamous cell carcinoma of the head and neck

CY Hsueh, HC Lau, Q Huang, H Gong, J Sun, P Cao… - Cancer, 2022 - Wiley Online Library
Background Dysbiosis of the laryngeal microbiota has been demonstrated to the
development of head and neck squamous cell carcinoma (HNSCC), but the association of …

Pepsin promotes activation of epidermal growth factor receptor and downstream oncogenic pathways, at slightly acidic and neutral pH, in exposed hypopharyngeal …

PG Doukas, DP Vageli, CT Sasaki… - International Journal of …, 2021 - mdpi.com
Pepsin refluxate is considered a risk factor for laryngopharyngeal carcinogenesis. Non-
acidic pepsin was previously linked to an inflammatory and tumorigenic effect on …

Head and neck cancers are not alike when tarred with the same brush: an epigenetic perspective from the cancerization field to prognosis

D Camuzi, TA Simão, F Dias, LF Ribeiro Pinto… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinomas affect different head and neck subsites and,
although these tumors arise from the same epithelial lining and share risk factors, they differ …

[HTML][HTML] Smoking signature is superior to programmed death-ligand 1 expression in predicting pathological response to neoadjuvant immunotherapy in lung cancer …

H Yang, W Ma, B Sun, L Fan, K Xu… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Background There is a paucity of biomarkers that can predict the degree of pathological
response [eg, pathological complete response (pCR) or major response (pMR)] to …