18F FDG PET/CT and Novel Molecular Imaging for Directing Immunotherapy in Cancer

DJ Hughes, M Subesinghe, B Taylor, A Bille, J Spicer… - Radiology, 2022 - pubs.rsna.org
Immunotherapy has transformed the treatment landscape of many cancers, with durable
responses in disease previously associated with a poor prognosis. Patient selection remains …

Primary tumor location in lung cancer: the evaluation and administration

X Xie, X Li, W Tang, P Xie, X Tan - Chinese Medical Journal, 2022 - mednexus.org
Lung cancer continues to be the leading cause of cancer-related death in the world, which is
classically subgrouped into two major histological types: Non-small cell lung cancer …

[HTML][HTML] Non-invasive measurement of PD-L1 status and prediction of immunotherapy response using deep learning of PET/CT images

W Mu, L Jiang, Y Shi, I Tunali, JE Gray… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Currently, only a fraction of patients with non-small cell lung cancer (NSCLC)
treated with immune checkpoint inhibitors (ICIs) experience a durable clinical benefit (DCB) …

Evaluation of PD-L1 Expression Level in Patients With Non-Small Cell Lung Cancer by 18F-FDG PET/CT Radiomics and Clinicopathological Characteristics

J Li, S Ge, S Sang, C Hu, S Deng - Frontiers in Oncology, 2021 - frontiersin.org
Purpose In the present study, we aimed to evaluate the expression of programmed death-
ligand 1 (PD-L1) in patients with non-small cell lung cancer (NSCLC) by radiomic features of …

[HTML][HTML] Radiomic biomarkers of tumor immune biology and immunotherapy response

JH Wang, KA Wahid, LV van Dijk, K Farahani… - Clinical and …, 2021 - Elsevier
Immunotherapies are leading to improved outcomes for many cancers, including those with
devastating prognoses. As therapies like immune checkpoint inhibitors (ICI) become a …

Predicting PD-L1 expression status in patients with non-small cell lung cancer using [18F]FDG PET/CT radiomics

X Zhao, Y Zhao, J Zhang, Z Zhang, L Liu, X Zhao - EJNMMI research, 2023 - Springer
Background In recent years, immune checkpoint inhibitor (ICI) therapy has greatly changed
the treatment prospects of patients with non-small cell lung cancer (NSCLC). Among the …

PET/CT molecular imaging in the era of immune-checkpoint inhibitors therapy

Y Gao, C Wu, X Chen, L Ma, X Zhang, J Chen… - Frontiers in …, 2022 - frontiersin.org
Cancer immunotherapy, especially immune-checkpoint inhibitors (ICIs), has paved a new
way for the treatment of many types of malignancies, particularly advanced-stage cancers …

[HTML][HTML] Deep learning radiomics model based on PET/CT predicts PD-L1 expression in non-small cell lung cancer

B Li, J Su, K Liu, C Hu - European Journal of Radiology Open, 2024 - Elsevier
Purpose Programmed cell death protein-1 ligand (PD-L1) is an important prognostic
predictor for immunotherapy of non-small cell lung cancer (NSCLC). This study aimed to …

Obesity is a risk factor for intrahepatic cholangiocarcinoma progression associated with alterations of metabolic activity and immune status

K Yugawa, S Itoh, N Iseda, T Kurihara, Y Kitamura… - Scientific reports, 2021 - nature.com
Body mass index (BMI) is well known to be associated with poor prognosis in several
cancers. The relationship between BMI and the long-term outcomes of patients with …

Clinical feasibility study of early 30-minute dynamic FDG-PET scanning protocol for patients with lung lesions

F Du, X Wumener, Y Zhang, M Zhang, J Zhao, J Zhou… - EJNMMI physics, 2024 - Springer
Purpose This study aimed to evaluate the clinical feasibility of early 30-minute dynamic 2-
deoxy-2-[18F] fluoro-D-glucose (18F-FDG) positron emission tomography (PET) scanning …