Existing reviews suggest that milk and other dairy products do not play a role in the
development of obesity in childhood, but they do make an important contribution to …

Obesity is a risk factor for colorectal cancer, and hyperinsulinemia, a common condition in
obese patients, may underlie this relationship. Insulin, in addition to its metabolic effects, has …

Insulin‐like growth factors (IGFs) and IGF binding proteins (IGFBPs) play an important role in
cell growth and differentiation. Clinical and epidemiological studies have indicated that …

Since human pituitary growth hormone (GH) became available for treatment in 1960,
followed in 1985 by recombinant human GH (rhGH), the diagnosis of GH deficiency (GHD) …

The effect of different feeding levels on plasma levels of insulin-like growth factor-I (IGF-I),
41kDa insulin-like growth factor binding protein (41kDa IGFBP), and growth hormone (GH) …

Abstract Context Pappalysins (PAPP-A, PAPP-A2) modulate body growth by increasing
insulin-like growth factor I (IGF-I) bioavailability through cleavage of insulin-like growth factor …

The factors regulating adrenarche are unknown. Recent in vitro studies have demonstrated
that insulin and insulin-like growth factor I induce major adrenal steroidogenic enzyme …

Although low GH levels are commonly seen in obese adults and children, the effects of
obesity on the insulin-like growth factor (IGF)/IGF-binding protein (IGFBP) system have not …

Pancreatic carcinoma is a leading cause of cancer deaths, and recent clinical trials of a
number of oncology therapeutics have not substantially improved clinical outcomes. We …

Background The hypothalamic‐pituitary‐gonadal (HPG) and hypothalamic‐pituitary‐
somatotropic (HPS) axes are strongly interconnected. Interactions between these axes are …