For nearly 30 years, the endogenous bioactivity of insulin-like growth factor I (IGF-I) has
been estimated by its circulating concentrations of immunoreactive IGF-I, obtained after …

Insulin-like growth factor I (IGF-I) is a major regulator of bone growth during childhood.
However, beyond knowledge that IGF-I influences longitudinal growth, its associations to …

Objectives To investigate the quality of life (QoL) in acromegalic patients in relation to
biochemical parameters. Design and methods Single-center, open label study in 14 …

Objective: Gynecomastia is defined as a benign proliferation of male breast glandular tissue.
Its prevalence during puberty varies between 50-60% and is also common in neonatal and …

Impaired GH activity at target tissues, occurring when GH action is blocked or during
suboptimal GH replacement therapy, may result in a pathological state associated with …

Verapamil promotes functional β-cell mass and improves glucose homeostasis in diabetic
mice and humans with type 1 diabetes (T1D). Now, our global proteomics analysis of serum …

Background Hypothyroidism is associated with obesity, and thyroid hormones are involved
in the regulation of body composition, including fat mass. Genome-wide association studies …

Objectives: African American children have greater bone mineral density (BMD) and bone
mineral content (BMC) than white children. We examined the hypothesis that differences in …