It is well established that protein–energy malnutrition decreases serum insulin-like growth
factor (IGF)-I levels, and supplementation of 30 g of whey protein daily has been shown to …

In this issue of the Journal, Ito and colleagues show that the proinflammatory state in severe
stages of chronic obstructive pulmonary disease (COPD) is related to chromatin unwinding …

Ob jec ti ve: Pubertal gynecomastia (PG) occurs in up to 65% of adolescent boys. In this
study, we investigated the relationship between the ages at which PG and peak height …

In mammals, the rate of somatic growth is rapid in early postnatal life but then slows with
age, approaching zero as the animal approaches adult body size. To investigate the …

Context: A method based on two GH-dependent markers, IGF-I and pro-collagen type III N-
terminal peptide (P-III-P), has been devised to detect exogenously administered GH …

Limited proteolysis of insulin-like growth factor binding protein-3 (IGFBP-3) is a fundamental
mechanism in the regulation of IGF-I bioavailability in the bloodstream. Its measurement by …

Human GH receptor (hGHR) was recently expressed on a Ba/F3 cell line, which is a mouse
pro-B cell lymphoma that has been induced to become a cloned cell line (Ba/F3-hGHR) …

Insulin-like growth factors I and II (IGF-I and IGF-II) are single chain peptides with a
molecular weight of 7649 and 7471 respectively. They show a high degree of sequence …

Objective. Metabolic bone disease (MBD) and muscle wasting (MW) are serious
complications in adult patients suffering from inflammatory bowel disease. These …

Circulating insulin-like growth factor I (IGF-I) levels are stable throughout the day and
correlate with pulsatile endogenous growth hormone (GH) secretion. A single measurement …