Tooth agenesis and tumor are two totally different diseases occurring at different ages. In the
past 10 years, more and more evidences suggested there was a relationship between them …

Wnt/β-catenin signaling pathway is strictly controlled by multiple negative regulators.
However, how tumor cells override the negative regulatory effects to maintain constitutive …

Abstract Background and Objective The Wnt/β-catenin signaling pathway has been
considered to be a factor in the development and progression of ovarian cancer. Methods All …

Background: The Wnt/β-catenin signaling pathway is an important regulator of cellular
functions suchas proliferation, survival and cell adhesion. Wnt/β-catenin signaling is …

Background Numerous studies have reported the correlation between AXIN2 polymorphism
and cancer risk, but the results seem not consistent. In order to get an overall, accurate and …

Abstract Axis inhibition protein 2 (Axin2) is a negative regulator of the canonical Wnt/β-
catenin signaling pathway, and functions as a tumor suppressor in a number of human …

The Wnt signaling pathway plays a crucial role in human cancer development, and axis
inhibition protein 2 (Axin2) is a master scaffold protein involved in Wnt signaling. Axin2 …

Aim: The aim of this study was to investigate the association of the rs2240308 and
rs1133683 polymorphisms in the AXIN2 gene with colorectal cancer (CRC) in Mexican …

BACKGROUND Treatment of prostate cancer (PCa) may be improved by identifying
biological mechanisms of tumor growth that directly impact clinical disease progression. We …

Plenty of epidemiological studies have assessed the effects of AXIN2 polymorphisms on the
risk of developing cancer, but the available results were somewhat inconclusive. Odds ratios …