Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis

V Pathade, S Nene, S Ratnam, DK Khatri… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …

Elucidating the role of hypoxia-inducible factor in rheumatoid arthritis

EM Sabi, A Singh, ZM Althafar, T Behl, A Sehgal… - …, 2022 - Springer
Rheumatoid arthritis (RA) is a chronic multifactorial disease, provocative, and degenerative
autoimmune condition that impacts millions of individuals around the globe. As a result of …

Identification and Mechanism Elucidation of Anti-Inflammatory Peptides in Jinhua Ham: An Integrative In Silico and In Vitro Study

X Dong, Y Ma, Y Xie, W Cui, H Zhou… - Journal of Agricultural …, 2023 - ACS Publications
This study aimed to effectively identify anti-inflammatory peptides in Jinhua ham, a dry-cured
meat product made from the hind legs of pigs by curing and fermenting processes, and …

[HTML][HTML] Going, Toll-like receptors in skin inflammation and inflammatory diseases

V Kumar - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Abstract The Indian Ayurvedic physicians knew the concept of inflammation dating back to
1500 BC. The continuous progress in the immunology of inflammation has explained its …

Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo

KE Nilsen, B Zhang, A Skjesol, L Ryan… - Life Science …, 2023 - life-science-alliance.org
Inflammation plays a crucial role in the development and progression of many diseases, and
is often caused by dysregulation of signalling from pattern recognition receptors, such as …

[HTML][HTML] SARS-CoV-2 pan-variant inhibitory peptides deter S1-ACE2 interaction and neutralize delta and omicron pseudoviruses

M Shah, SU Moon, JH Kim, TT Thao, HG Woo - Computational and …, 2022 - Elsevier
Approved neutralizing antibodies that target the prototype Spike are losing their potency
against the emerging variants of concern (VOCs) of SARS-CoV-2, particularly Omicron …

Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo

M Korinek, PS Hsieh, YL Chen, PW Hsieh… - Biochemical …, 2021 - Elsevier
Psoriasis is a long-lasting inflammatory skin disease lacking proper cure. Dysregulated
activation of neutrophils is a major pathogenic factor in psoriasis. Formyl peptide receptor 1 …

[HTML][HTML] Osthole inhibits expression of genes associated with toll-like receptor 2 signaling pathway in an organotypic 3D skin model of human epidermis with atopic …

NK Kordulewska, J Topa, R Stryiński, B Jarmołowska - Cells, 2021 - mdpi.com
The Toll-like receptor (TLR) family signature has been linked to the etiopathology of atopic
dermatitis (AD), a chronic inflammatory skin disease associated with skin barrier dysfunction …

[HTML][HTML] Differential expression of endogenous retroviruses and inflammatory mediators in female and male offspring in a mouse model of maternal immune activation

C Cipriani, AM Tartaglione, M Giudice… - International Journal of …, 2022 - mdpi.com
Maternal infections during pregnancy and the consequent maternal immune activation (MIA)
are the major risk factors for autism spectrum disorder (ASD). Epidemiological evidence is …

Toll-like receptor and silk sericin for tissue engineering

SG Kim, HY Kweon, YY Jo - International Journal of Industrial …, 2021 - koreascience.kr
Toll-like receptor (TLR) is responsible for the recognition of foreign protein. Accordingly, TLR
is mainly expressed in the immune associated cells. When foreign protein such as silk …