[HTML][HTML] Beneficial and detrimental effects of reactive oxygen species on lifespan: a comprehensive review of comparative and experimental studies
HJ Shields, A Traa, JM Van Raamsdonk - Frontiers in cell and …, 2021 - frontiersin.org
Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …
neurodegeneration and cancer. Despite decades of research dedicated to understanding …
Cellular mechanisms of liver fibrosis
The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …
Therapeutics data commons: Machine learning datasets and tasks for drug discovery and development
Therapeutics machine learning is an emerging field with incredible opportunities for
innovatiaon and impact. However, advancement in this field requires formulation of …
innovatiaon and impact. However, advancement in this field requires formulation of …
[HTML][HTML] Review of NAD (P) H-dependent oxidoreductases: Properties, engineering and application
Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …
Electrochemical transformations catalyzed by cytochrome P450s and peroxidases
Cytochrome P450s (Cyt P450s) and peroxidases are enzymes featuring iron heme cofactors
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …
that have wide applicability as biocatalysts in chemical syntheses. Cyt P450s are a family of …
The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
Mitochondria are critical for metabolic homeostasis of the liver, and their dysfunction is a
major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a …
major cause of liver diseases. Optic atrophy 1 (OPA1) is a mitochondrial fusion protein with a …
A chemical perspective on the clinical use of platinum-based anticancer drugs
S Alassadi, MJ Pisani, NJ Wheate - Dalton Transactions, 2022 - pubs.rsc.org
Platinum drugs have been a mainstay of cancer chemotherapy since the introduction of
cisplatin in the 1970s. Since then, carboplatin and oxaliplatin have been approved world …
cisplatin in the 1970s. Since then, carboplatin and oxaliplatin have been approved world …
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer
Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …
numerous structurally and functionally different chemotherapeutic agents. MDR is …
Phytochemistry, pharmacological activities and uses of traditional medicinal plant Kaempferia galanga L.–An overview
A Kumar - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Kaempferia galanga L. is a stemless, rhizomatous,
aromatic, perennial and indigenous herb. It is native to India and distributed in China …
aromatic, perennial and indigenous herb. It is native to India and distributed in China …
Nutraceuticals' novel formulations: the good, the bad, the unknown and patents involved
Traditional nutraceuticals and cosmeceuticals hold pragmatic nature with respect to their
definitions, claims, purposes and marketing strategies. Their definitions are not well …
definitions, claims, purposes and marketing strategies. Their definitions are not well …